The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores

M. A. Crawford; N. M. Casperd; A. J. Sinclair

doi:10.1016/0305-0491(76)90264-9

The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores

M. A. Crawford
, N. M. Casperd
, A. J. Sinclair

Research output: Contribution to journal › Article › Research › peer-review

224 Citations (Scopus)

Abstract

1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.

Original language	English
Pages (from-to)	395-401
Number of pages	7
Journal	Comparative Biochemistry and Physiology Part B: Comparative Biochemistry
Volume	54
Issue number	3
DOIs	https://doi.org/10.1016/0305-0491(76)90264-9
Publication status	Published - 1 Jan 1976
Externally published	Yes

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title = "The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores",

abstract = "1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.",

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T1 - The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores

AU - Crawford, M. A.

AU - Casperd, N. M.

AU - Sinclair, A. J.

PY - 1976/1/1

Y1 - 1976/1/1

N2 - 1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.

AB - 1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.

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DO - 10.1016/0305-0491(76)90264-9

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JO - Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

JF - Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

IS - 3

ER -

The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores

Abstract

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