Abstract
Zidovudine, or 3'-azido-3‘deoxythymidine, formerly known as azidothymidine (AZT; BW A509U), is an analog of the nucleoside thymidine. Zidovudine is a potent inhibitor of the HIV reverse transcriptase and has proven efficacy in the treatment and prevention of HIV infection. It was the first antiretroviral compound to be licensed for the treatment of people infected with HIV. The compound was synthesized much earlier, however, by Horwitz and colleagues (1964) and subsequently used in anticancer research.
| Original language | English |
|---|---|
| Title of host publication | Kucers the Use of Antibiotics |
| Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs |
| Editors | M. Lindsay Grayson |
| Place of Publication | Boca Raton FL USA |
| Publisher | CRC Press |
| Pages | 3657-3697 |
| Number of pages | 41 |
| Edition | 7th |
| ISBN (Electronic) | 9781498747967 |
| ISBN (Print) | 9781498747950 |
| Publication status | Published - 2 Oct 2017 |
