Zebrafish: A Versatile Animal Model for Fertility Research

Hoo Jing Ying, Yatinesh Kumari, Mohd Farooq Shaikh, Seow Mun Hue, Bey Hing Goh

    Research output: Contribution to journalReview ArticleResearchpeer-review

    22 Citations (Scopus)

    Abstract

    The utilization of zebrafish in biomedical research is very common in the research world nowadays. Today, it has emerged as a favored vertebrate organism for the research in science of reproduction. There is a significant growth in amount numbers of scientific literature pertaining to research discoveries in reproductive sciences in zebrafish. It has implied the importance of zebrafish in this particular field of research. In essence, the current available literature has covered from the very specific brain region or neurons of zebrafish, which are responsible for reproductive regulation, until the gonadal level of the animal. The discoveries and findings have proven that this small animal is sharing a very close/similar reproductive system with mammals. More interestingly, the behavioral characteristics and along with the establishment of animal courtship behavior categorization in zebrafish have laid an even stronger foundation and firmer reason on the suitability of zebrafish utilization in research of reproductive sciences. In view of the immense importance of this small animal for the development of reproductive sciences, this review aimed at compiling and describing the proximate close similarity of reproductive regulation on zebrafish and human along with factors contributing to the infertility, showing its versatility and its potential usage for fertility research.

    Original languageEnglish
    Article number9732780
    Number of pages21
    JournalBioMed Research International
    Volume2016
    DOIs
    Publication statusPublished - 31 Jul 2016

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