Zebrafish: A Versatile Animal Model for Fertility Research

Hoo Jing Ying, Yatinesh Kumari, Mohd Farooq Shaikh, Seow Mun Hue, Bey Hing Goh

Research output: Contribution to journalReview ArticleResearchpeer-review

41 Citations (Scopus)

Abstract

The utilization of zebrafish in biomedical research is very common in the research world nowadays. Today, it has emerged as a favored vertebrate organism for the research in science of reproduction. There is a significant growth in amount numbers of scientific literature pertaining to research discoveries in reproductive sciences in zebrafish. It has implied the importance of zebrafish in this particular field of research. In essence, the current available literature has covered from the very specific brain region or neurons of zebrafish, which are responsible for reproductive regulation, until the gonadal level of the animal. The discoveries and findings have proven that this small animal is sharing a very close/similar reproductive system with mammals. More interestingly, the behavioral characteristics and along with the establishment of animal courtship behavior categorization in zebrafish have laid an even stronger foundation and firmer reason on the suitability of zebrafish utilization in research of reproductive sciences. In view of the immense importance of this small animal for the development of reproductive sciences, this review aimed at compiling and describing the proximate close similarity of reproductive regulation on zebrafish and human along with factors contributing to the infertility, showing its versatility and its potential usage for fertility research.

Original languageEnglish
Article number9732780
Number of pages21
JournalBioMed Research International
Volume2016
DOIs
Publication statusPublished - 31 Jul 2016

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