YB-1: the Jekyll and Hyde of kidney disease?

Phillip Kantharidis; Mark E. Cooper

doi:10.1016/j.kint.2023.10.020

YB-1: the Jekyll and Hyde of kidney disease?

Phillip Kantharidis, Mark E. Cooper

Diabetes

Research output: Contribution to journal › Comment / Debate › Other › peer-review

1 Citation (Scopus)

Abstract

Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.

Original language	English
Pages (from-to)	18-20
Number of pages	3
Journal	Kidney International
Volume	105
Issue number	1
DOIs	https://doi.org/10.1016/j.kint.2023.10.020
Publication status	Published - Jan 2024

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10.1016/j.kint.2023.10.020

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title = "YB-1: the Jekyll and Hyde of kidney disease?",

abstract = "Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.",

author = "Phillip Kantharidis and Cooper, \{Mark E.\}",

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year = "2024",

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T2 - the Jekyll and Hyde of kidney disease?

AU - Kantharidis, Phillip

AU - Cooper, Mark E.

PY - 2024/1

Y1 - 2024/1

N2 - Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.

AB - Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.

UR - https://www.scopus.com/pages/publications/85180282130

U2 - 10.1016/j.kint.2023.10.020

DO - 10.1016/j.kint.2023.10.020

M3 - Comment / Debate

AN - SCOPUS:85180282130

SN - 0085-2538

VL - 105

SP - 18

EP - 20

JO - Kidney International

JF - Kidney International

IS - 1

ER -

YB-1: the Jekyll and Hyde of kidney disease?

Abstract

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