TY - JOUR
T1 - YB-1
T2 - the Jekyll and Hyde of kidney disease?
AU - Kantharidis, Phillip
AU - Cooper, Mark E.
N1 - Publisher Copyright:
© 2023
PY - 2024/1
Y1 - 2024/1
N2 - Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.
AB - Y-box–binding protein 1 is a well-described and important regulator of gene transcription, which is linked to various pathologic conditions, including inflammation and fibrosis of the kidney. The identification of a novel and protective crosstalk pathway between podocytes and tubular cells in the kidney with Y-box–binding protein 1 acting as a paracrine messenger sheds new light and provides novel opportunities for renoprotection.
UR - http://www.scopus.com/inward/record.url?scp=85180282130&partnerID=8YFLogxK
U2 - 10.1016/j.kint.2023.10.020
DO - 10.1016/j.kint.2023.10.020
M3 - Comment / Debate
AN - SCOPUS:85180282130
SN - 0085-2538
VL - 105
SP - 18
EP - 20
JO - Kidney International
JF - Kidney International
IS - 1
ER -