Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010

Rebecca Lipsitz; Susan Garges; Rosemarie Aurigemma; Prasith Baccam; David D Blaney; Allen Cheuk-Seng Cheng; Bart J Currie; David A B Dance; Jay E Gee; Joseph C Larsen; Direk Limmathurotsakul; Meredith G Morrow; Robert Norton; Elizabeth O'Mara; Sharon J Peacock; Nicki T Pesik; L Paige Rogers; Herbert P Schweizer; Ivo Steinmetz; Gladys Gek Yen Tan; Patrick Tan; W J Wiersinga; Vannaporn Wuthiekanun; Terry L Smith

doi:10.3201/eid1812.120638

Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010

Rebecca Lipsitz, Susan Garges, Rosemarie Aurigemma, Prasith Baccam, David D Blaney, Allen Cheuk-Seng Cheng, Bart J Currie, David A B Dance, Jay E Gee, Joseph C Larsen, Direk Limmathurotsakul, Meredith G Morrow, Robert Norton, Elizabeth O'Mara, Sharon J Peacock, Nicki T Pesik, L Paige Rogers, Herbert P Schweizer, Ivo Steinmetz, Gladys Gek Yen TanPatrick Tan, W J Wiersinga, Vannaporn Wuthiekanun, Terry L Smith

Epidemiology and Preventive Medicine Alfred Hospital

Research output: Contribution to journal › Article › Other

147 Citations (Scopus)

Abstract

The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options.

Original language	English
Pages (from-to)	e2
Number of pages	1
Journal	Emerging Infectious Diseases
Volume	18
Issue number	12
DOIs	https://doi.org/10.3201/eid1812.120638
Publication status	Published - 2012

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10.3201/eid1812.120638

Cite this

Lipsitz, R., Garges, S., Aurigemma, R., Baccam, P., Blaney, D. D., Cheng, A. C-S., Currie, B. J., Dance, D. A. B., Gee, J. E., Larsen, J. C., Limmathurotsakul, D., Morrow, M. G., Norton, R., O'Mara, E., Peacock, S. J., Pesik, N. T., Rogers, L. P., Schweizer, H. P., Steinmetz, I., ... Smith, T. L. (2012). Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010. Emerging Infectious Diseases, 18(12), e2. https://doi.org/10.3201/eid1812.120638

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title = "Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010",

abstract = "The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options.",

author = "Rebecca Lipsitz and Susan Garges and Rosemarie Aurigemma and Prasith Baccam and Blaney, {David D} and Cheng, {Allen Cheuk-Seng} and Currie, {Bart J} and Dance, {David A B} and Gee, {Jay E} and Larsen, {Joseph C} and Direk Limmathurotsakul and Morrow, {Meredith G} and Robert Norton and Elizabeth O'Mara and Peacock, {Sharon J} and Pesik, {Nicki T} and Rogers, {L Paige} and Schweizer, {Herbert P} and Ivo Steinmetz and Tan, {Gladys Gek Yen} and Patrick Tan and Wiersinga, {W J} and Vannaporn Wuthiekanun and Smith, {Terry L}",

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Lipsitz, R, Garges, S, Aurigemma, R, Baccam, P, Blaney, DD, Cheng, AC-S, Currie, BJ, Dance, DAB, Gee, JE, Larsen, JC, Limmathurotsakul, D, Morrow, MG, Norton, R, O'Mara, E, Peacock, SJ, Pesik, NT, Rogers, LP, Schweizer, HP, Steinmetz, I, Tan, GGY, Tan, P, Wiersinga, WJ, Wuthiekanun, V & Smith, TL 2012, 'Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010', Emerging Infectious Diseases, vol. 18, no. 12, pp. e2. https://doi.org/10.3201/eid1812.120638

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T1 - Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010

AU - Lipsitz, Rebecca

AU - Garges, Susan

AU - Aurigemma, Rosemarie

AU - Baccam, Prasith

AU - Blaney, David D

AU - Cheng, Allen Cheuk-Seng

AU - Currie, Bart J

AU - Dance, David A B

AU - Gee, Jay E

AU - Larsen, Joseph C

AU - Limmathurotsakul, Direk

AU - Morrow, Meredith G

AU - Norton, Robert

AU - O'Mara, Elizabeth

AU - Peacock, Sharon J

AU - Pesik, Nicki T

AU - Rogers, L Paige

AU - Schweizer, Herbert P

AU - Steinmetz, Ivo

AU - Tan, Gladys Gek Yen

AU - Tan, Patrick

AU - Wiersinga, W J

AU - Wuthiekanun, Vannaporn

AU - Smith, Terry L

PY - 2012

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N2 - The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options.

AB - The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options.

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DO - 10.3201/eid1812.120638

M3 - Article

C2 - 23171644

VL - 18

SP - e2

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 12

ER -