Wolbachia and virus protection in insects

Lauren Hedges, Jeremy Brownlie, Scott Leslie O'Neill, Karyn Johnson

Research output: Contribution to journalArticleResearchpeer-review

706 Citations (Scopus)


Wolbachia pipientis bacteria are common endosymbionts of insects that are best known for their ability to increase their prevalence in populations by manipulating host reproductive systems. However, there are examples of Wolbachia that exist in nature that seem to induce no reproductive parasitism trait and yet are able to invade populations. We demonstrate a fitness benefit for Wolbachia-infected insects that may explain this paradox. Drosophila melanogaster flies infected with Wolbachia are less susceptible to mortality induced by a range of RNA viruses. The antiviral protection associated with Wolbachia infection might be exploited in future strategies to reduce transmission of pathogens by insects.
Original languageEnglish
Pages (from-to)702 - 702
Number of pages1
Issue number5902
Publication statusPublished - 2008
Externally publishedYes

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