Wide-field in situ multiplexed raman imaging with superresolution

Houkai Chen, Xiaojing Wu, Yuquan Zhang, Yong Yang, Changjun Min, Siwei Zhu, Xiaocong Yuan, Qiaoliang Bao, Jing Bu

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.

Original languageEnglish
Pages (from-to)530-534
Number of pages5
JournalPhotonics Research
Volume6
Issue number6
DOIs
Publication statusPublished - 1 Jun 2018
Externally publishedYes

Cite this

Chen, H., Wu, X., Zhang, Y., Yang, Y., Min, C., Zhu, S., ... Bu, J. (2018). Wide-field in situ multiplexed raman imaging with superresolution. Photonics Research, 6(6), 530-534. https://doi.org/10.1364/PRJ.6.000530
Chen, Houkai ; Wu, Xiaojing ; Zhang, Yuquan ; Yang, Yong ; Min, Changjun ; Zhu, Siwei ; Yuan, Xiaocong ; Bao, Qiaoliang ; Bu, Jing. / Wide-field in situ multiplexed raman imaging with superresolution. In: Photonics Research. 2018 ; Vol. 6, No. 6. pp. 530-534.
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Chen, H, Wu, X, Zhang, Y, Yang, Y, Min, C, Zhu, S, Yuan, X, Bao, Q & Bu, J 2018, 'Wide-field in situ multiplexed raman imaging with superresolution', Photonics Research, vol. 6, no. 6, pp. 530-534. https://doi.org/10.1364/PRJ.6.000530

Wide-field in situ multiplexed raman imaging with superresolution. / Chen, Houkai; Wu, Xiaojing; Zhang, Yuquan; Yang, Yong; Min, Changjun; Zhu, Siwei; Yuan, Xiaocong; Bao, Qiaoliang; Bu, Jing.

In: Photonics Research, Vol. 6, No. 6, 01.06.2018, p. 530-534.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Chen, Houkai

AU - Wu, Xiaojing

AU - Zhang, Yuquan

AU - Yang, Yong

AU - Min, Changjun

AU - Zhu, Siwei

AU - Yuan, Xiaocong

AU - Bao, Qiaoliang

AU - Bu, Jing

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AB - Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.

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Chen H, Wu X, Zhang Y, Yang Y, Min C, Zhu S et al. Wide-field in situ multiplexed raman imaging with superresolution. Photonics Research. 2018 Jun 1;6(6):530-534. https://doi.org/10.1364/PRJ.6.000530