Abstract
Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.
Original language | English |
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Pages (from-to) | 530-534 |
Number of pages | 5 |
Journal | Photonics Research |
Volume | 6 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Jun 2018 |
Externally published | Yes |
Cite this
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Wide-field in situ multiplexed raman imaging with superresolution. / Chen, Houkai; Wu, Xiaojing; Zhang, Yuquan; Yang, Yong; Min, Changjun; Zhu, Siwei; Yuan, Xiaocong; Bao, Qiaoliang; Bu, Jing.
In: Photonics Research, Vol. 6, No. 6, 01.06.2018, p. 530-534.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Wide-field in situ multiplexed raman imaging with superresolution
AU - Chen, Houkai
AU - Wu, Xiaojing
AU - Zhang, Yuquan
AU - Yang, Yong
AU - Min, Changjun
AU - Zhu, Siwei
AU - Yuan, Xiaocong
AU - Bao, Qiaoliang
AU - Bu, Jing
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.
AB - Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.
UR - http://www.scopus.com/inward/record.url?scp=85048238394&partnerID=8YFLogxK
U2 - 10.1364/PRJ.6.000530
DO - 10.1364/PRJ.6.000530
M3 - Article
VL - 6
SP - 530
EP - 534
JO - Photonics Research
JF - Photonics Research
SN - 2327-9125
IS - 6
ER -