Wide-field in situ multiplexed raman imaging with superresolution

Houkai Chen; Xiaojing Wu; Yuquan Zhang; Yong Yang; Changjun Min; Siwei Zhu; Xiaocong Yuan; Qiaoliang Bao; Jing Bu

doi:10.1364/PRJ.6.000530

Wide-field in situ multiplexed raman imaging with superresolution

Houkai Chen, Xiaojing Wu, Yuquan Zhang, Yong Yang, Changjun Min, Siwei Zhu, Xiaocong Yuan, Qiaoliang Bao, Jing Bu

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.

Original language	English
Pages (from-to)	530-534
Number of pages	5
Journal	Photonics Research
Volume	6
Issue number	6
DOIs	https://doi.org/10.1364/PRJ.6.000530
Publication status	Published - 1 Jun 2018
Externally published	Yes

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10.1364/PRJ.6.000530

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Cite this

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title = "Wide-field in situ multiplexed raman imaging with superresolution",

abstract = "Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.",

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T1 - Wide-field in situ multiplexed raman imaging with superresolution

AU - Chen, Houkai

AU - Wu, Xiaojing

AU - Zhang, Yuquan

AU - Yang, Yong

AU - Min, Changjun

AU - Zhu, Siwei

AU - Yuan, Xiaocong

AU - Bao, Qiaoliang

AU - Bu, Jing

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.

AB - Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surfaceenhanced Raman scattering (SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields.

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EP - 534

JO - Photonics Research

JF - Photonics Research

SN - 2327-9125

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