Whole-Organism Analysis by Vibrational Spectroscopy

Dale Christensen, Anja Rudiether, Kamila Kochan, Bayden Wood

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)


Vibrational spectroscopy has contributed to the understanding of biological materials for many years. As the technology has advanced, the technique has been brought to bear on the analysis of whole organisms. Here, we discuss advanced and recently developed infrared and Raman spectroscopic instrumentation to whole-organism analysis. We highlight many of the recent contributions made in this relatively new area of spectroscopy, particularly addressing organisms associated with disease with emphasis on diagnosis and treatment. The application of vibrational spectroscopic techniques to entire organisms is still in its infancy, but new developments in imaging and chemometric processing will likely expand in the field in the near future.

Original languageEnglish
Pages (from-to)89-108
Number of pages20
JournalAnnual Review of Analytical Chemistry
Publication statusPublished - 12 Jun 2019


  • infrared spectroscopy
  • insects
  • parasites
  • Raman spectroscopy
  • yeasts

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