Whole-heart cine MRI using real-time respiratory self-gating

Sergio Uribe, Vivek Muthurangu, Redha Boubertakh, Tobias Schaeffter, Reza Razavi, Derek L.G. Hill, Michael S. Hansen

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)


Two-dimensional (2D) breath-hold cine MRI is used to assess cardiac anatomy and function. However, this technique requires cooperation from the patient, and in some cases the scan planning is complicated. Isotropic nonangulated three-dimensional (3D) cardiac MR can overcome some of these problems because it requires minimal planning and can be reformatted in any plane. However, current methods, even those that use undersampling techniques, involve breath-holding for periods that are too long for many patients. Free-breathing respiratory gating sequences represent a possible solution for realizing 3D cine imaging. A real-time respiratory self-gating technique for whole-heart cine MRI is presented. The technique enables assessment of cardiac anatomy and function with minimum planning or patient cooperation. Nonangulated isotropic 3D data were acquired from five healthy volunteers and then reformatted into 2D clinical views. The respiratory self-gating technique is shown to improve image quality in free-breathing scanning. In addition, ventricular volumetric data obtained using the 3D approach were comparable to those acquired with the conventional multislice 2D approach.

Original languageEnglish
Pages (from-to)606-613
Number of pages8
JournalMagnetic Resonance in Medicine
Issue number3
Publication statusPublished - Mar 2007
Externally publishedYes


  • Cine MRI
  • Free breathing
  • Respiratory gating
  • Self navigation
  • Whole-heart imaging

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