Water-soluble and pH-responsive polymeric nanotubes from cyclic peptide templates

Robert Chapman; Gregory G. Warr; Sebastien Perrier; Katrina A. Jolliffe

doi:10.1002/chem.201203602

Water-soluble and pH-responsive polymeric nanotubes from cyclic peptide templates

Robert Chapman, Gregory G. Warr, Sebastien Perrier, Katrina A. Jolliffe

Research output: Contribution to journal › Article › Research › peer-review

48 Citations (Scopus)

Abstract

Water-soluble organic nanotubes were prepared by convergently conjugating polymers of hydroxyethyl acrylate (HEA) and acrylic acid (AA) to self-assembling cyclic octapeptides of alternating d and l chirality. The structure of the self-assembled tubes was characterised in a number of polar solvents, and notably water, by using light scattering, TEM and small angle neutron scattering (SANS) techniques. In addition, the self-assembly into tubes could be controlled by exploiting the pH responsiveness of acrylic acid polymers.

Original language	English
Pages (from-to)	1955-1961
Number of pages	7
Journal	Chemistry - A European Journal
Volume	19
Issue number	6
DOIs	https://doi.org/10.1002/chem.201203602
Publication status	Published - 4 Feb 2013
Externally published	Yes

Keywords

nanotubes
peptides
polymers
self-assembly

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10.1002/chem.201203602

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Water-soluble and pH-responsive polymeric nanotubes from cyclic peptide templates

Abstract

Keywords

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