Waking up too early – the consequences of preterm birth on sleep development

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

Good quality sleep of sufficient duration is vital for optimal physiological function and our health. Sleep deprivation is associated with impaired neurocognitive function and emotional control, and increases the risk for cardiometabolic diseases, obesity and cancer. Sleep develops during fetal life with the emergence of a recognisable pattern of sleep states in the preterm fetus associated with the development, maturation and connectivity within neural networks in the brain. Despite the physiological importance of sleep, surprisingly little is known about how sleep develops in individuals born preterm. Globally, an estimated 15 million babies are born preterm (<37 weeks gestation) each year, and these babies are at significant risk of neural injury and impaired brain development. This review discusses how sleep develops during fetal and neonatal life, how preterm birth impacts on sleep development to adulthood, and the factors which may contribute to impaired brain and sleep development, leading to altered neurocognitive, behavioural and motor capabilities in the infant and child. Going forward, the challenge is to identify specific risk factors for impaired sleep development in preterm babies to allow for the design of interventions that will improve the quality and quantity of sleep throughout life. (Figure presented.).

Original languageEnglish
Pages (from-to)5687-5708
Number of pages22
JournalJournal of Physiology
Volume596
Issue number23
DOIs
Publication statusPublished - 1 Dec 2018

Keywords

  • neurodevelopment
  • perinatal
  • preterm
  • sleep

Cite this

@article{18220d4d88484f7abbd093ae2abb8e60,
title = "Waking up too early – the consequences of preterm birth on sleep development",
abstract = "Good quality sleep of sufficient duration is vital for optimal physiological function and our health. Sleep deprivation is associated with impaired neurocognitive function and emotional control, and increases the risk for cardiometabolic diseases, obesity and cancer. Sleep develops during fetal life with the emergence of a recognisable pattern of sleep states in the preterm fetus associated with the development, maturation and connectivity within neural networks in the brain. Despite the physiological importance of sleep, surprisingly little is known about how sleep develops in individuals born preterm. Globally, an estimated 15 million babies are born preterm (<37 weeks gestation) each year, and these babies are at significant risk of neural injury and impaired brain development. This review discusses how sleep develops during fetal and neonatal life, how preterm birth impacts on sleep development to adulthood, and the factors which may contribute to impaired brain and sleep development, leading to altered neurocognitive, behavioural and motor capabilities in the infant and child. Going forward, the challenge is to identify specific risk factors for impaired sleep development in preterm babies to allow for the design of interventions that will improve the quality and quantity of sleep throughout life. (Figure presented.).",
keywords = "neurodevelopment, perinatal, preterm, sleep",
author = "Laura Bennet and Walker, {David W.} and Horne, {Rosemary S.C.}",
year = "2018",
month = "12",
day = "1",
doi = "10.1113/JP274950",
language = "English",
volume = "596",
pages = "5687--5708",
journal = "The Journal of Physiology",
issn = "0022-3751",
publisher = "Wiley-Blackwell",
number = "23",

}

Waking up too early – the consequences of preterm birth on sleep development. / Bennet, Laura; Walker, David W.; Horne, Rosemary S.C.

In: Journal of Physiology, Vol. 596, No. 23, 01.12.2018, p. 5687-5708.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Waking up too early – the consequences of preterm birth on sleep development

AU - Bennet, Laura

AU - Walker, David W.

AU - Horne, Rosemary S.C.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Good quality sleep of sufficient duration is vital for optimal physiological function and our health. Sleep deprivation is associated with impaired neurocognitive function and emotional control, and increases the risk for cardiometabolic diseases, obesity and cancer. Sleep develops during fetal life with the emergence of a recognisable pattern of sleep states in the preterm fetus associated with the development, maturation and connectivity within neural networks in the brain. Despite the physiological importance of sleep, surprisingly little is known about how sleep develops in individuals born preterm. Globally, an estimated 15 million babies are born preterm (<37 weeks gestation) each year, and these babies are at significant risk of neural injury and impaired brain development. This review discusses how sleep develops during fetal and neonatal life, how preterm birth impacts on sleep development to adulthood, and the factors which may contribute to impaired brain and sleep development, leading to altered neurocognitive, behavioural and motor capabilities in the infant and child. Going forward, the challenge is to identify specific risk factors for impaired sleep development in preterm babies to allow for the design of interventions that will improve the quality and quantity of sleep throughout life. (Figure presented.).

AB - Good quality sleep of sufficient duration is vital for optimal physiological function and our health. Sleep deprivation is associated with impaired neurocognitive function and emotional control, and increases the risk for cardiometabolic diseases, obesity and cancer. Sleep develops during fetal life with the emergence of a recognisable pattern of sleep states in the preterm fetus associated with the development, maturation and connectivity within neural networks in the brain. Despite the physiological importance of sleep, surprisingly little is known about how sleep develops in individuals born preterm. Globally, an estimated 15 million babies are born preterm (<37 weeks gestation) each year, and these babies are at significant risk of neural injury and impaired brain development. This review discusses how sleep develops during fetal and neonatal life, how preterm birth impacts on sleep development to adulthood, and the factors which may contribute to impaired brain and sleep development, leading to altered neurocognitive, behavioural and motor capabilities in the infant and child. Going forward, the challenge is to identify specific risk factors for impaired sleep development in preterm babies to allow for the design of interventions that will improve the quality and quantity of sleep throughout life. (Figure presented.).

KW - neurodevelopment

KW - perinatal

KW - preterm

KW - sleep

UR - http://www.scopus.com/inward/record.url?scp=85057520736&partnerID=8YFLogxK

U2 - 10.1113/JP274950

DO - 10.1113/JP274950

M3 - Review Article

VL - 596

SP - 5687

EP - 5708

JO - The Journal of Physiology

JF - The Journal of Physiology

SN - 0022-3751

IS - 23

ER -