Voluntary weight loss: Systematic review of early phase body composition changes

Steven Heymsfield, Diana Thomas, Alison Martin Nguyen, J Peng, C K Martin, Wei Shen, Boyd Strauss, Anja Bosy-westphal, M J Muller

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)


Weight loss follows when adult humans enter a phase of negative energy balance brought about by reducing energy intake and/or increasing energy expenditure. The weight loss period is usually viewed as a continuous process, ending when energy equilibrium is achieved at a lower weight or with death following depletion of fuel stores. However, growing evidence supports the expanded view that induction of negative energy balance leads to well-defined physiological effects characterized by three discrete phases (I-III). At present there are no comprehensive reviews of the early phase of weight loss, a gap highlighted by recent interest in rapidly testing new treatments with short-term protocols.
Original languageEnglish
Pages (from-to)e348 - e361
Number of pages14
JournalObesity Reviews
Issue number5
Publication statusPublished - 2011

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