Volumetric differences in the anterior cingulate cortex prospectively predict alcohol-related problems in adolescence

Ali Cheetham, Nicholas Brian Allen, Sarah Whittle, Julian G Simmons, Murat Yucel, Dan Lubman

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)


Individual differences in brain structure and function are suggested to exist prior to the onset of alcohol abuse. Cross-sectional studies have demonstrated abnormalities in brain regions underlying affective processes that may form a pathway to the emergence of later alcohol abuse and dependence in vulnerable individuals. However, no prospective studies have examined whether these abnormalities predict later problems with alcohol. Objective: This study aims to examine whether individual differences in affect and brain volume prospectively predict alcohol-related problems in adolescence.
Original languageEnglish
Pages (from-to)1731 - 1742
Number of pages12
Issue number8
Publication statusPublished - 2014

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