Vitamin D is independently associated with depression in overweight women with and without PCOS

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Abstract

Background: Depression, anxiety, and inflammation are common in polycystic ovary syndrome (PCOS). Inflammation may adversely impact on mood and vitamin D has been associated with both mood disorders and inflammation in the general population, but these relationships have not been studied in PCOS. The aim of this study was to investigate the association among 25 hydroxy-Vitamin D (25OHVD) status, anxiety, depression, and inflammation in women with and without PCOS. Methods: Cross-sectional study in overweight or obese premenopausal women with (n=50) and without (n=23) PCOS. Primary outcome measures were 25OHVD, mood (Hospital Anxiety and Depression questionnaire), and inflammation (highly sensitive C-reactive protein (hsCRP)). Results: Vitamin D deficiency (25OHVD
Original languageEnglish
Pages (from-to)179 - 182
Number of pages4
JournalGynecological Endocrinology
Volume31
Issue number3
DOIs
Publication statusPublished - 2015

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