Visuospatial asymmetries arise from differences in the onset time of perceptual evidence accumulation

Daniel P. Newman, Gerard M. Loughnane, Simon P. Kelly, Redmond G. O’Connell, Mark A. Bellgrove

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Healthy subjects tend to exhibit a bias of visual attention whereby left hemifield stimuli are processed more quickly and accurately than stimuli appearing in the right hemifield. It has long been held that this phenomenon arises from the dominant role of the right cerebral hemisphere in regulating attention. However, methods that would enable more precise understanding of the mechanisms underpinning visuospatial bias have remained elusive. We sought to finely trace the temporal evolution of spatial biases by leveraging a novel bilateral dot motion detection paradigm. In combination with electroencephalography, this paradigm enables researchers to isolate discrete neural signals reflecting the key neural processes needed for making these detection decisions. These include signals for spatial attention, early target selection, evidence accumulation, and motor preparation. Using this method, we established that three key neural markers accounted for unique between-subject variation in visuospatial bias: hemispheric asymmetry in posterior α power measured before target onset, which is related to the distribution of preparatory attention across the visual field; asymmetry in the peak latency of the early N2c target-selection signal; and, finally, asymmetry in the onset time of the subsequent neural evidence-accumulation process with earlier onsets for left hemifield targets. Our development of a single paradigm to dissociate distinct processing components that track the temporal evolution of spatial biases not only advances our understanding of the neural mechanisms underpinning normal visuospatial attention bias, but may also in the future aid differential diagnoses in disorders of spatial attention.

Original languageEnglish
Pages (from-to)3378-3385
Number of pages8
JournalJournal of Neuroscience
Volume37
Issue number12
DOIs
Publication statusPublished - 22 Mar 2017

Keywords

  • Asymmetry
  • Decision making
  • EEG
  • Evidence accumulation
  • Pseudoneglect
  • Spatial attention

Cite this

@article{2464983a0e194a8eaefbe74ba947ab22,
title = "Visuospatial asymmetries arise from differences in the onset time of perceptual evidence accumulation",
abstract = "Healthy subjects tend to exhibit a bias of visual attention whereby left hemifield stimuli are processed more quickly and accurately than stimuli appearing in the right hemifield. It has long been held that this phenomenon arises from the dominant role of the right cerebral hemisphere in regulating attention. However, methods that would enable more precise understanding of the mechanisms underpinning visuospatial bias have remained elusive. We sought to finely trace the temporal evolution of spatial biases by leveraging a novel bilateral dot motion detection paradigm. In combination with electroencephalography, this paradigm enables researchers to isolate discrete neural signals reflecting the key neural processes needed for making these detection decisions. These include signals for spatial attention, early target selection, evidence accumulation, and motor preparation. Using this method, we established that three key neural markers accounted for unique between-subject variation in visuospatial bias: hemispheric asymmetry in posterior α power measured before target onset, which is related to the distribution of preparatory attention across the visual field; asymmetry in the peak latency of the early N2c target-selection signal; and, finally, asymmetry in the onset time of the subsequent neural evidence-accumulation process with earlier onsets for left hemifield targets. Our development of a single paradigm to dissociate distinct processing components that track the temporal evolution of spatial biases not only advances our understanding of the neural mechanisms underpinning normal visuospatial attention bias, but may also in the future aid differential diagnoses in disorders of spatial attention.",
keywords = "Asymmetry, Decision making, EEG, Evidence accumulation, Pseudoneglect, Spatial attention",
author = "Newman, {Daniel P.} and Loughnane, {Gerard M.} and Kelly, {Simon P.} and O’Connell, {Redmond G.} and Bellgrove, {Mark A.}",
year = "2017",
month = "3",
day = "22",
doi = "10.1523/JNEUROSCI.3512-16.2017",
language = "English",
volume = "37",
pages = "3378--3385",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "12",

}

Visuospatial asymmetries arise from differences in the onset time of perceptual evidence accumulation. / Newman, Daniel P.; Loughnane, Gerard M.; Kelly, Simon P.; O’Connell, Redmond G.; Bellgrove, Mark A.

In: Journal of Neuroscience, Vol. 37, No. 12, 22.03.2017, p. 3378-3385.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Visuospatial asymmetries arise from differences in the onset time of perceptual evidence accumulation

AU - Newman, Daniel P.

AU - Loughnane, Gerard M.

AU - Kelly, Simon P.

AU - O’Connell, Redmond G.

AU - Bellgrove, Mark A.

PY - 2017/3/22

Y1 - 2017/3/22

N2 - Healthy subjects tend to exhibit a bias of visual attention whereby left hemifield stimuli are processed more quickly and accurately than stimuli appearing in the right hemifield. It has long been held that this phenomenon arises from the dominant role of the right cerebral hemisphere in regulating attention. However, methods that would enable more precise understanding of the mechanisms underpinning visuospatial bias have remained elusive. We sought to finely trace the temporal evolution of spatial biases by leveraging a novel bilateral dot motion detection paradigm. In combination with electroencephalography, this paradigm enables researchers to isolate discrete neural signals reflecting the key neural processes needed for making these detection decisions. These include signals for spatial attention, early target selection, evidence accumulation, and motor preparation. Using this method, we established that three key neural markers accounted for unique between-subject variation in visuospatial bias: hemispheric asymmetry in posterior α power measured before target onset, which is related to the distribution of preparatory attention across the visual field; asymmetry in the peak latency of the early N2c target-selection signal; and, finally, asymmetry in the onset time of the subsequent neural evidence-accumulation process with earlier onsets for left hemifield targets. Our development of a single paradigm to dissociate distinct processing components that track the temporal evolution of spatial biases not only advances our understanding of the neural mechanisms underpinning normal visuospatial attention bias, but may also in the future aid differential diagnoses in disorders of spatial attention.

AB - Healthy subjects tend to exhibit a bias of visual attention whereby left hemifield stimuli are processed more quickly and accurately than stimuli appearing in the right hemifield. It has long been held that this phenomenon arises from the dominant role of the right cerebral hemisphere in regulating attention. However, methods that would enable more precise understanding of the mechanisms underpinning visuospatial bias have remained elusive. We sought to finely trace the temporal evolution of spatial biases by leveraging a novel bilateral dot motion detection paradigm. In combination with electroencephalography, this paradigm enables researchers to isolate discrete neural signals reflecting the key neural processes needed for making these detection decisions. These include signals for spatial attention, early target selection, evidence accumulation, and motor preparation. Using this method, we established that three key neural markers accounted for unique between-subject variation in visuospatial bias: hemispheric asymmetry in posterior α power measured before target onset, which is related to the distribution of preparatory attention across the visual field; asymmetry in the peak latency of the early N2c target-selection signal; and, finally, asymmetry in the onset time of the subsequent neural evidence-accumulation process with earlier onsets for left hemifield targets. Our development of a single paradigm to dissociate distinct processing components that track the temporal evolution of spatial biases not only advances our understanding of the neural mechanisms underpinning normal visuospatial attention bias, but may also in the future aid differential diagnoses in disorders of spatial attention.

KW - Asymmetry

KW - Decision making

KW - EEG

KW - Evidence accumulation

KW - Pseudoneglect

KW - Spatial attention

UR - http://www.scopus.com/inward/record.url?scp=85016065695&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.3512-16.2017

DO - 10.1523/JNEUROSCI.3512-16.2017

M3 - Article

VL - 37

SP - 3378

EP - 3385

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 12

ER -