Visualizing cancer cell chemotaxis and invasion in 2D and 3D

Olivia Susanto; Andrew J. Muinonen-Martin; Max Nobis; Robert H. Insall

doi:10.1007/978-1-4939-3480-5_17

Visualizing cancer cell chemotaxis and invasion in 2D and 3D

Olivia Susanto, Andrew J. Muinonen-Martin, Max Nobis, Robert H. Insall

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

4 Citations (Scopus)

Abstract

We describe three chemotaxis assays—Insall chambers, circular invasion assays, and 3D organotypic assays— that are particularly appropriate for measuring migration of cancer cells in response to gradients of soluble attractants. Each assay has defined advantages, and together they provide the best possible quantitative assessment of cancer chemotaxis.

Original language	English
Title of host publication	Methods in Molecular Biology
Editors	Tian Jin, Dale Hereld
Place of Publication	New York, NY
Publisher	Humana Press
Chapter	17
Pages	217-228
Number of pages	12
ISBN (Electronic)	9781493934805
ISBN (Print)	9781493934782
DOIs	https://doi.org/10.1007/978-1-4939-3480-5_17
Publication status	Published - 1 Jan 2016
Externally published	Yes

Publication series

Name	Methods in Molecular Biology
Volume	1407
ISSN (Print)	1064-3745
ISSN (Electronic)	1940-6029

Keywords

Cell migration
Chemotaxis
Invasion
Melanoma
Metastasis
Organotypic

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-1-4939-3480-5_17

Cite this

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title = "Visualizing cancer cell chemotaxis and invasion in 2D and 3D",

abstract = "We describe three chemotaxis assays—Insall chambers, circular invasion assays, and 3D organotypic assays— that are particularly appropriate for measuring migration of cancer cells in response to gradients of soluble attractants. Each assay has defined advantages, and together they provide the best possible quantitative assessment of cancer chemotaxis.",

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Visualizing cancer cell chemotaxis and invasion in 2D and 3D. / Susanto, Olivia; Muinonen-Martin, Andrew J.; Nobis, Max et al.
Methods in Molecular Biology. ed. / Tian Jin; Dale Hereld. New York, NY: Humana Press, 2016. p. 217-228 (Methods in Molecular Biology; Vol. 1407).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

TY - CHAP

T1 - Visualizing cancer cell chemotaxis and invasion in 2D and 3D

AU - Susanto, Olivia

AU - Muinonen-Martin, Andrew J.

AU - Nobis, Max

AU - Insall, Robert H.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - We describe three chemotaxis assays—Insall chambers, circular invasion assays, and 3D organotypic assays— that are particularly appropriate for measuring migration of cancer cells in response to gradients of soluble attractants. Each assay has defined advantages, and together they provide the best possible quantitative assessment of cancer chemotaxis.

AB - We describe three chemotaxis assays—Insall chambers, circular invasion assays, and 3D organotypic assays— that are particularly appropriate for measuring migration of cancer cells in response to gradients of soluble attractants. Each assay has defined advantages, and together they provide the best possible quantitative assessment of cancer chemotaxis.

KW - Cell migration

KW - Chemotaxis

KW - Invasion

KW - Melanoma

KW - Metastasis

KW - Organotypic

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DO - 10.1007/978-1-4939-3480-5_17

M3 - Chapter (Book)

C2 - 27271906

AN - SCOPUS:84990219688

SN - 9781493934782

T3 - Methods in Molecular Biology

SP - 217

EP - 228

BT - Methods in Molecular Biology

A2 - Jin, Tian

A2 - Hereld, Dale

PB - Humana Press

CY - New York, NY

ER -

Visualizing cancer cell chemotaxis and invasion in 2D and 3D

Abstract

Publication series

Keywords

UN SDGs

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