Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Research output: Contribution to journalArticleResearchpeer-review

Abstract

We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.

Original languageEnglish
Pages (from-to)12076-12079
Number of pages4
JournalChemical Communications
Volume53
Issue number89
DOIs
Publication statusPublished - 2017

Cite this

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title = "Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock",
abstract = "We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.",
author = "Truong, {Vinh X.} and Fanyi Li and Francesca Ercole and Forsythe, {John S.}",
year = "2017",
doi = "10.1039/c7cc07257k",
language = "English",
volume = "53",
pages = "12076--12079",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "The Royal Society of Chemistry",
number = "89",

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Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock. / Truong, Vinh X.; Li, Fanyi; Ercole, Francesca; Forsythe, John S.

In: Chemical Communications, Vol. 53, No. 89, 2017, p. 12076-12079.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Truong, Vinh X.

AU - Li, Fanyi

AU - Ercole, Francesca

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AB - We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.

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