Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Vinh X. Truong; Fanyi Li; Francesca Ercole; John S. Forsythe

doi:10.1039/c7cc07257k

Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Vinh X. Truong, Fanyi Li, Francesca Ercole, John S. Forsythe

Research output: Contribution to journal › Article › Research › peer-review

18 Citations (Scopus)

Abstract

We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.

Original language	English
Pages (from-to)	12076-12079
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	89
DOIs	https://doi.org/10.1039/c7cc07257k
Publication status	Published - 2017

Access to Document

10.1039/c7cc07257k

Cite this

@article{f90c9bf6d5bd42d89f85f62687c54856,

title = "Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock",

abstract = "We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.",

author = "Truong, {Vinh X.} and Fanyi Li and Francesca Ercole and Forsythe, {John S.}",

year = "2017",

doi = "10.1039/c7cc07257k",

language = "English",

volume = "53",

pages = "12076--12079",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "The Royal Society of Chemistry",

number = "89",

}

TY - JOUR

T1 - Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

AU - Truong, Vinh X.

AU - Li, Fanyi

AU - Ercole, Francesca

AU - Forsythe, John S.

PY - 2017

Y1 - 2017

N2 - We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.

AB - We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.

UR - http://www.scopus.com/inward/record.url?scp=85033212898&partnerID=8YFLogxK

U2 - 10.1039/c7cc07257k

DO - 10.1039/c7cc07257k

M3 - Article

AN - SCOPUS:85033212898

SN - 1359-7345

VL - 53

SP - 12076

EP - 12079

JO - Chemical Communications

JF - Chemical Communications

IS - 89

ER -

Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Abstract

Access to Document

Other files and links

Cite this