Virtual Histology: A Window to the Heart of Atherosclerosis

J. Layland, A. M. Wilson, I. Lim, R. J. Whitbourn

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)


Intravascular ultrasound has done much to improve our understanding of atherosclerosis and the impact of percutaneous intervention on the coronary artery. However, subjectivity in interpreting the acoustic reflection of the ultrasound signal has spawned the development of other progressive technologies. Virtual histology intravascular ultrasound (VHIVUS) utilises the ultrasound backscatter signal in order to colour code plaque into four pre-specified subtypes based on their histological composition. We review the background behind traditional grey scale intravascular ultrasound (IVUS) and examine the current evidence for VHIVUS and its potential for use in clinical interventional practice.

Original languageEnglish
Pages (from-to)615-621
Number of pages7
JournalHeart Lung and Circulation
Issue number10
Publication statusPublished - 1 Oct 2011
Externally publishedYes


  • Atherosclerosis
  • Intravascular ultrasound
  • Percutaneous intervention
  • Plaque

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