TY - JOUR
T1 - Very preterm infants failing CPAP show signs of fatigue immediately after birth
AU - Siew, Melissa Li-Lian
AU - van Vonderen, Jeroen J
AU - Hooper, Stuart Brian
AU - Te Pas, Arjan B
PY - 2015
Y1 - 2015
N2 - OBJECTIVE: To investigate the differences in breathing pattern and effort in infants at birth who failed or succeeded on continuous positive airway pressure (CPAP) during the first 48 hours after birth. METHODS: Respiratory function recordings of 32 preterm infants were reviewed of which 15 infants with a gestational age of 28.6 (0.7) weeks failed CPAP and 17 infants with a GA of 30.1 (0.4) weeks did not fail CPAP. Frequency, duration and tidal volumes (VT) of expiratory holds (EHs), peak inspiratory flows, CPAP-level and FiO2-levels were analysed. RESULTS: EH incidence increased 9 ml/kg) with higher peak inspiratory flows than CPAP-fail infants (71.8 +/- 15.8 vs. 15.5 +/- 5.2 ml/kg.s, p
AB - OBJECTIVE: To investigate the differences in breathing pattern and effort in infants at birth who failed or succeeded on continuous positive airway pressure (CPAP) during the first 48 hours after birth. METHODS: Respiratory function recordings of 32 preterm infants were reviewed of which 15 infants with a gestational age of 28.6 (0.7) weeks failed CPAP and 17 infants with a GA of 30.1 (0.4) weeks did not fail CPAP. Frequency, duration and tidal volumes (VT) of expiratory holds (EHs), peak inspiratory flows, CPAP-level and FiO2-levels were analysed. RESULTS: EH incidence increased 9 ml/kg) with higher peak inspiratory flows than CPAP-fail infants (71.8 +/- 15.8 vs. 15.5 +/- 5.2 ml/kg.s, p
UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460041/pdf/pone.0129592.pdf
U2 - 10.1371/journal.pone.0129592
DO - 10.1371/journal.pone.0129592
M3 - Article
SN - 1932-6203
VL - 10
JO - PLoS ONE
JF - PLoS ONE
IS - 6
M1 - e0129592
ER -