TY - JOUR
T1 - Veno-right ventricular cannulation reduces recirculation in extracorporeal membrane oxygenation
AU - Lindstrom, Steven James
AU - Mennen, M
AU - Rosenfeldt, Franklin Lawrence
AU - Salmonsen, R F
PY - 2012
Y1 - 2012
N2 - Background: Veno-venous extracorporeal membrane oxygenation has several advantages over veno-arterial support for patients with severe reversible respiratory failure. However, recirculation can limit oxygen delivery as pump flow increases. This could be ameliorated by placing the return catheter in the right ventricle instead of the central veins. We compared recirculation in veno-right ventricular support with that in conventional veno-venous support and its relationship with pump flow. Methods: Five greyhound dogs were sequentially cannulated percutaneously for both veno-venous and veno-right ventricular support. Recirculation was measured by comparing oxygen levels in the circuit drainage and return lines before and immediately after a sudden increase in circuit oxygenation at pump flows between 0.5 L/min and 4 L/min for both modalities. Results: Recirculation was reduced in veno-right ventricular support compared with conventional veno-venous support at 4 L/min pump flow (8.4 versus 37.9 , p=0.0076) and increased less with increases in pump flow (2.9 per 1 L/min vs. 11.1 per 1 L/min, p
AB - Background: Veno-venous extracorporeal membrane oxygenation has several advantages over veno-arterial support for patients with severe reversible respiratory failure. However, recirculation can limit oxygen delivery as pump flow increases. This could be ameliorated by placing the return catheter in the right ventricle instead of the central veins. We compared recirculation in veno-right ventricular support with that in conventional veno-venous support and its relationship with pump flow. Methods: Five greyhound dogs were sequentially cannulated percutaneously for both veno-venous and veno-right ventricular support. Recirculation was measured by comparing oxygen levels in the circuit drainage and return lines before and immediately after a sudden increase in circuit oxygenation at pump flows between 0.5 L/min and 4 L/min for both modalities. Results: Recirculation was reduced in veno-right ventricular support compared with conventional veno-venous support at 4 L/min pump flow (8.4 versus 37.9 , p=0.0076) and increased less with increases in pump flow (2.9 per 1 L/min vs. 11.1 per 1 L/min, p
UR - http://prf.sagepub.com/content/27/6/464.full.pdf
U2 - 10.1177/0267659112450744
DO - 10.1177/0267659112450744
M3 - Article
VL - 27
SP - 464
EP - 469
JO - Perfusion
JF - Perfusion
SN - 0267-6591
IS - 6
ER -