Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries

E. Van Rymenant; C. Grootaert; K. Beerens; P. W. Needs; P. A. Kroon; A. Kerimi; G. Williamson; R. García-Villalba; A. González-Sarrías; F. Tomas-Barberan; J. Van Camp; J. Van de Voorde

doi:10.1039/C7FO01273J

Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries

E. Van Rymenant, C. Grootaert, K. Beerens, P. W. Needs, P. A. Kroon, A. Kerimi, G. Williamson, R. García-Villalba, A. González-Sarrías, F. Tomas-Barberan, J. Van Camp, J. Van de Voorde

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Abstract

Polyphenols are beneficial for health, but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin, urolithins and ferulic acid-4-O-sulfate-not their glucuronidated forms or ferulic acid-caused vasorelaxation. Therefore, we advise the use of relevant conjugates in future mechanistic research.

Original language	English
Pages (from-to)	4331-4335
Number of pages	5
Journal	Food & Function
Volume	8
Issue number	12
DOIs	https://doi.org/10.1039/C7FO01273J
Publication status	Published - 1 Dec 2017
Externally published	Yes

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10.1039/C7FO01273J

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Van Rymenant, E., Grootaert, C., Beerens, K., Needs, P. W., Kroon, P. A., Kerimi, A., Williamson, G., García-Villalba, R., González-Sarrías, A., Tomas-Barberan, F., Van Camp, J., & Van de Voorde, J. (2017). Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. Food & Function, 8(12), 4331-4335. https://doi.org/10.1039/C7FO01273J

Van Rymenant, E. ; Grootaert, C. ; Beerens, K. ; Needs, P. W. ; Kroon, P. A. ; Kerimi, A. ; Williamson, G. ; García-Villalba, R. ; González-Sarrías, A. ; Tomas-Barberan, F. ; Van Camp, J. ; Van de Voorde, J. / Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. In: Food & Function. 2017 ; Vol. 8, No. 12. pp. 4331-4335.

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title = "Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries",

abstract = "Polyphenols are beneficial for health, but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin, urolithins and ferulic acid-4-O-sulfate-not their glucuronidated forms or ferulic acid-caused vasorelaxation. Therefore, we advise the use of relevant conjugates in future mechanistic research.",

author = "{Van Rymenant}, E. and C. Grootaert and K. Beerens and Needs, {P. W.} and Kroon, {P. A.} and A. Kerimi and G. Williamson and R. Garc{\'i}a-Villalba and A. Gonz{\'a}lez-Sarr{\'i}as and F. Tomas-Barberan and {Van Camp}, J. and {Van de Voorde}, J.",

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doi = "10.1039/C7FO01273J",

language = "English",

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Van Rymenant, E, Grootaert, C, Beerens, K, Needs, PW, Kroon, PA, Kerimi, A, Williamson, G, García-Villalba, R, González-Sarrías, A, Tomas-Barberan, F, Van Camp, J & Van de Voorde, J 2017, 'Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries', Food & Function, vol. 8, no. 12, pp. 4331-4335. https://doi.org/10.1039/C7FO01273J

Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. / Van Rymenant, E.; Grootaert, C.; Beerens, K.; Needs, P. W.; Kroon, P. A.; Kerimi, A.; Williamson, G.; García-Villalba, R.; González-Sarrías, A.; Tomas-Barberan, F.; Van Camp, J.; Van de Voorde, J.

In: Food & Function, Vol. 8, No. 12, 01.12.2017, p. 4331-4335.

Research output: Contribution to journal › Article › Research › peer-review

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T1 - Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries

AU - Van Rymenant, E.

AU - Grootaert, C.

AU - Beerens, K.

AU - Needs, P. W.

AU - Kroon, P. A.

AU - Kerimi, A.

AU - Williamson, G.

AU - García-Villalba, R.

AU - González-Sarrías, A.

AU - Tomas-Barberan, F.

AU - Van Camp, J.

AU - Van de Voorde, J.

PY - 2017/12/1

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AB - Polyphenols are beneficial for health, but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin, urolithins and ferulic acid-4-O-sulfate-not their glucuronidated forms or ferulic acid-caused vasorelaxation. Therefore, we advise the use of relevant conjugates in future mechanistic research.

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JO - Food & Function

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ER -

Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries

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