Vasomotor symptoms and urogenital atrophy in older women: a systematic review

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective Our aim was to systematically review published articles for the prevalence of persistent estrogen depletion symptoms among women aged 65+ years. Methods A systematic literature search of English-language publications was performed using MEDLINE, EMBASE, CINAHL, and PsycINFO. Twenty-three studies that included information on the prevalence of vasomotor and/or urogenital atrophy symptoms among older women (65 + years) met our inclusion criteria. Risk of bias of the included studies was assessed using a risk-of-bias tool explicitly designed for the systematic review of prevalence studies. Results The available data suggest that vasomotor symptoms are experienced by a considerable proportion of older women, that symptoms of urogenital atrophy including urinary incontinence are widespread, and that women remain sexually active well into later life. A high degree of variability was observed for the prevalence of estrogen deficiency symptoms for women age 65+ years. Discrepancies in modes of recruitment, sampling procedures, time frames over which symptoms were assessed and use of different and non-validated assessment tools contributed to the inconsistencies across the published studies. Conclusion Larger and appropriately sampled studies, employing validated questionnaires, are still needed to establish the prevalence of persistent estrogen depletion symptoms in women aged 65+ years.
Original languageEnglish
Pages (from-to)112 - 120
Number of pages9
JournalClimacteric
Volume18
Issue number2
DOIs
Publication statusPublished - 2015

Cite this

@article{d6eb6c42d70e4e108a84eb9cdd38c9c9,
title = "Vasomotor symptoms and urogenital atrophy in older women: a systematic review",
abstract = "Objective Our aim was to systematically review published articles for the prevalence of persistent estrogen depletion symptoms among women aged 65+ years. Methods A systematic literature search of English-language publications was performed using MEDLINE, EMBASE, CINAHL, and PsycINFO. Twenty-three studies that included information on the prevalence of vasomotor and/or urogenital atrophy symptoms among older women (65 + years) met our inclusion criteria. Risk of bias of the included studies was assessed using a risk-of-bias tool explicitly designed for the systematic review of prevalence studies. Results The available data suggest that vasomotor symptoms are experienced by a considerable proportion of older women, that symptoms of urogenital atrophy including urinary incontinence are widespread, and that women remain sexually active well into later life. A high degree of variability was observed for the prevalence of estrogen deficiency symptoms for women age 65+ years. Discrepancies in modes of recruitment, sampling procedures, time frames over which symptoms were assessed and use of different and non-validated assessment tools contributed to the inconsistencies across the published studies. Conclusion Larger and appropriately sampled studies, employing validated questionnaires, are still needed to establish the prevalence of persistent estrogen depletion symptoms in women aged 65+ years.",
author = "Zeleke, {Berihun Megabiaw} and Davis, {Susan Ruth} and Pamela Fradkin and Bell, {Robin Jean}",
year = "2015",
doi = "10.3109/13697137.2014.978754",
language = "English",
volume = "18",
pages = "112 -- 120",
journal = "Climacteric",
issn = "1369-7137",
publisher = "Taylor & Francis",
number = "2",

}

Vasomotor symptoms and urogenital atrophy in older women: a systematic review. / Zeleke, Berihun Megabiaw; Davis, Susan Ruth; Fradkin, Pamela; Bell, Robin Jean.

In: Climacteric, Vol. 18, No. 2, 2015, p. 112 - 120.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Vasomotor symptoms and urogenital atrophy in older women: a systematic review

AU - Zeleke, Berihun Megabiaw

AU - Davis, Susan Ruth

AU - Fradkin, Pamela

AU - Bell, Robin Jean

PY - 2015

Y1 - 2015

N2 - Objective Our aim was to systematically review published articles for the prevalence of persistent estrogen depletion symptoms among women aged 65+ years. Methods A systematic literature search of English-language publications was performed using MEDLINE, EMBASE, CINAHL, and PsycINFO. Twenty-three studies that included information on the prevalence of vasomotor and/or urogenital atrophy symptoms among older women (65 + years) met our inclusion criteria. Risk of bias of the included studies was assessed using a risk-of-bias tool explicitly designed for the systematic review of prevalence studies. Results The available data suggest that vasomotor symptoms are experienced by a considerable proportion of older women, that symptoms of urogenital atrophy including urinary incontinence are widespread, and that women remain sexually active well into later life. A high degree of variability was observed for the prevalence of estrogen deficiency symptoms for women age 65+ years. Discrepancies in modes of recruitment, sampling procedures, time frames over which symptoms were assessed and use of different and non-validated assessment tools contributed to the inconsistencies across the published studies. Conclusion Larger and appropriately sampled studies, employing validated questionnaires, are still needed to establish the prevalence of persistent estrogen depletion symptoms in women aged 65+ years.

AB - Objective Our aim was to systematically review published articles for the prevalence of persistent estrogen depletion symptoms among women aged 65+ years. Methods A systematic literature search of English-language publications was performed using MEDLINE, EMBASE, CINAHL, and PsycINFO. Twenty-three studies that included information on the prevalence of vasomotor and/or urogenital atrophy symptoms among older women (65 + years) met our inclusion criteria. Risk of bias of the included studies was assessed using a risk-of-bias tool explicitly designed for the systematic review of prevalence studies. Results The available data suggest that vasomotor symptoms are experienced by a considerable proportion of older women, that symptoms of urogenital atrophy including urinary incontinence are widespread, and that women remain sexually active well into later life. A high degree of variability was observed for the prevalence of estrogen deficiency symptoms for women age 65+ years. Discrepancies in modes of recruitment, sampling procedures, time frames over which symptoms were assessed and use of different and non-validated assessment tools contributed to the inconsistencies across the published studies. Conclusion Larger and appropriately sampled studies, employing validated questionnaires, are still needed to establish the prevalence of persistent estrogen depletion symptoms in women aged 65+ years.

UR - http://informahealthcare.com/doi/pdf/10.3109/13697137.2014.978754

U2 - 10.3109/13697137.2014.978754

DO - 10.3109/13697137.2014.978754

M3 - Article

VL - 18

SP - 112

EP - 120

JO - Climacteric

JF - Climacteric

SN - 1369-7137

IS - 2

ER -