Variations in reporting of outcomes in randomized trials on diet and physical activity in pregnancy: A systematic review

Ewelina Rogozińska, Nadine Marlin, Fen Yang, Jodie M Dodd, Kym Guelfi, Helena Teede, Fernanda Garanhani Surita, Dorte M. Jensen, Nina Rica Wium Geiker, Arne Astrup, SeonAe Yeo, Tarja I Kinnunen, Signe Nilssen Stafne, Jose Guilherme Cecatti, Annick Bogaerts, Hans Hauner, Ben Willem Mol, Tânia T. Scudeller, Christina Anne Vinter, Kristina M. RenaultRoland Devlieger, Shakila Thangaratinam, Khalid S Khan

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Abstract

Aim: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy. Methods: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes. We defined the quality of reporting as a proportion using a six-item questionnaire. Regression analysis was used to identify factors affecting this quality. Results: Sixty-six randomized controlled trials were published in 78 papers (66 main, 12 secondary). Gestational diabetes (57.6%, 38/66), preterm birth (48.5%, 32/66) and cesarian section (60.6%, 40/66), were the commonly reported 'critically important' outcomes. Gestational weight gain (84.5%, 56/66) and birth weight (87.9%, 58/66) were reported in most papers, although not considered critically important. The median quality of reporting was 0.60 (interquartile range 0.25, 0.83) for a maximum score of one. Study and journal characteristics did not affect quality. Conclusion: Many studies on lifestyle interventions in pregnancy do not report critically important outcomes, highlighting the need for core outcome set development.

Original languageEnglish
Pages (from-to)1101-1110
Number of pages10
JournalThe Journal of Obstetrics and Gynaecology Research
Volume43
Issue number7
DOIs
Publication statusPublished - Jul 2017

Keywords

  • Diet
  • Outcome
  • Physical activity
  • Pregnancy
  • Quality
  • Randomized trial

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