Validating injury burden estimates using population birth cohorts and longitudinal cohort studies of injury outcomes

The VIBES-Junior study protocol

Belinda J Gabbe, Joanna F Dipnall, John W Lynch, Frederick P Rivara, Ronan A Lyons, Shanthi Ameratunga, Mariana Brussoni, Fiona E Lecky, Clare Bradley, Pam M Simpson, Ben Beck, Joanne C Demmler, Jane Lyons, Amy Schneeberg, James E Harrison

Research output: Contribution to journalArticleOtherpeer-review

Abstract

Introduction Traumatic injury is a leading contributor to the global disease burden in children and adolescents, but methods used to estimate burden do not account for differences in patterns of injury and recovery between children and adults. A lack of empirical data on postinjury disability in children has limited capacity to derive valid disability weights and describe the long-term individual and societal impacts of injury in the early part of life. The aim of this study is to establish valid estimates of the burden of non-fatal injury in children and adolescents. Methods and analysis Five longitudinal studies of paediatric injury survivors 18 years at the time of injury (Australia, Canada, UK and USA) and two whole-of-population linked administrative data paediatric studies (Australia and Wales) will be analysed over a 3-year period commencing 2018. Meta-analysis of deidentified patient-level data (2,600) from five injury-specific longitudinal studies (Victorian State Trauma Registry; Victorian Orthopaedic Trauma Outcomes Registry; UK Burden of Injury; British Columbia Children's Hospital Longitudinal Injury Outcomes; Children's Health After Injury) and >1 million children from two whole-of-population cohorts (South Australian Early Childhood Data Project and Wales Electronic Cohort for Children). Systematic analysis of pooled injury-specific cohort data using a variety of statistical techniques, and parallel analysis of whole-of-population cohorts, will be used to develop estimated disability weights for years lost due to disability, establish appropriate injury classifications and explore factors influencing recovery. Ethics and dissemination The project was approved by the Monash University Human Research Ethics Committee project number 12 311. Results of this study will be submitted for publication in internationally peer-reviewed journals. The findings from this project have the capacity to improve the validity of paediatric injury burden measurements in future local and global burden of disease studies.

Original languageEnglish
Article numbere024755
Number of pages7
JournalBMJ Open
Volume8
Issue number8
DOIs
Publication statusPublished - 1 Aug 2018

Keywords

  • epidemiology
  • paediatrics
  • public health
  • trauma management

Cite this

Gabbe, Belinda J ; Dipnall, Joanna F ; Lynch, John W ; Rivara, Frederick P ; Lyons, Ronan A ; Ameratunga, Shanthi ; Brussoni, Mariana ; Lecky, Fiona E ; Bradley, Clare ; Simpson, Pam M ; Beck, Ben ; Demmler, Joanne C ; Lyons, Jane ; Schneeberg, Amy ; Harrison, James E. / Validating injury burden estimates using population birth cohorts and longitudinal cohort studies of injury outcomes : The VIBES-Junior study protocol. In: BMJ Open. 2018 ; Vol. 8, No. 8.
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abstract = "Introduction Traumatic injury is a leading contributor to the global disease burden in children and adolescents, but methods used to estimate burden do not account for differences in patterns of injury and recovery between children and adults. A lack of empirical data on postinjury disability in children has limited capacity to derive valid disability weights and describe the long-term individual and societal impacts of injury in the early part of life. The aim of this study is to establish valid estimates of the burden of non-fatal injury in children and adolescents. Methods and analysis Five longitudinal studies of paediatric injury survivors 18 years at the time of injury (Australia, Canada, UK and USA) and two whole-of-population linked administrative data paediatric studies (Australia and Wales) will be analysed over a 3-year period commencing 2018. Meta-analysis of deidentified patient-level data (2,600) from five injury-specific longitudinal studies (Victorian State Trauma Registry; Victorian Orthopaedic Trauma Outcomes Registry; UK Burden of Injury; British Columbia Children's Hospital Longitudinal Injury Outcomes; Children's Health After Injury) and >1 million children from two whole-of-population cohorts (South Australian Early Childhood Data Project and Wales Electronic Cohort for Children). Systematic analysis of pooled injury-specific cohort data using a variety of statistical techniques, and parallel analysis of whole-of-population cohorts, will be used to develop estimated disability weights for years lost due to disability, establish appropriate injury classifications and explore factors influencing recovery. Ethics and dissemination The project was approved by the Monash University Human Research Ethics Committee project number 12 311. Results of this study will be submitted for publication in internationally peer-reviewed journals. The findings from this project have the capacity to improve the validity of paediatric injury burden measurements in future local and global burden of disease studies.",
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author = "Gabbe, {Belinda J} and Dipnall, {Joanna F} and Lynch, {John W} and Rivara, {Frederick P} and Lyons, {Ronan A} and Shanthi Ameratunga and Mariana Brussoni and Lecky, {Fiona E} and Clare Bradley and Simpson, {Pam M} and Ben Beck and Demmler, {Joanne C} and Jane Lyons and Amy Schneeberg and Harrison, {James E}",
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Gabbe, BJ, Dipnall, JF, Lynch, JW, Rivara, FP, Lyons, RA, Ameratunga, S, Brussoni, M, Lecky, FE, Bradley, C, Simpson, PM, Beck, B, Demmler, JC, Lyons, J, Schneeberg, A & Harrison, JE 2018, 'Validating injury burden estimates using population birth cohorts and longitudinal cohort studies of injury outcomes: The VIBES-Junior study protocol', BMJ Open, vol. 8, no. 8, e024755. https://doi.org/10.1136/bmjopen-2018-024755

Validating injury burden estimates using population birth cohorts and longitudinal cohort studies of injury outcomes : The VIBES-Junior study protocol. / Gabbe, Belinda J; Dipnall, Joanna F; Lynch, John W; Rivara, Frederick P; Lyons, Ronan A; Ameratunga, Shanthi ; Brussoni, Mariana; Lecky, Fiona E; Bradley, Clare; Simpson, Pam M; Beck, Ben; Demmler, Joanne C; Lyons, Jane; Schneeberg, Amy; Harrison, James E.

In: BMJ Open, Vol. 8, No. 8, e024755, 01.08.2018.

Research output: Contribution to journalArticleOtherpeer-review

TY - JOUR

T1 - Validating injury burden estimates using population birth cohorts and longitudinal cohort studies of injury outcomes

T2 - The VIBES-Junior study protocol

AU - Gabbe, Belinda J

AU - Dipnall, Joanna F

AU - Lynch, John W

AU - Rivara, Frederick P

AU - Lyons, Ronan A

AU - Ameratunga, Shanthi

AU - Brussoni, Mariana

AU - Lecky, Fiona E

AU - Bradley, Clare

AU - Simpson, Pam M

AU - Beck, Ben

AU - Demmler, Joanne C

AU - Lyons, Jane

AU - Schneeberg, Amy

AU - Harrison, James E

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Introduction Traumatic injury is a leading contributor to the global disease burden in children and adolescents, but methods used to estimate burden do not account for differences in patterns of injury and recovery between children and adults. A lack of empirical data on postinjury disability in children has limited capacity to derive valid disability weights and describe the long-term individual and societal impacts of injury in the early part of life. The aim of this study is to establish valid estimates of the burden of non-fatal injury in children and adolescents. Methods and analysis Five longitudinal studies of paediatric injury survivors 18 years at the time of injury (Australia, Canada, UK and USA) and two whole-of-population linked administrative data paediatric studies (Australia and Wales) will be analysed over a 3-year period commencing 2018. Meta-analysis of deidentified patient-level data (2,600) from five injury-specific longitudinal studies (Victorian State Trauma Registry; Victorian Orthopaedic Trauma Outcomes Registry; UK Burden of Injury; British Columbia Children's Hospital Longitudinal Injury Outcomes; Children's Health After Injury) and >1 million children from two whole-of-population cohorts (South Australian Early Childhood Data Project and Wales Electronic Cohort for Children). Systematic analysis of pooled injury-specific cohort data using a variety of statistical techniques, and parallel analysis of whole-of-population cohorts, will be used to develop estimated disability weights for years lost due to disability, establish appropriate injury classifications and explore factors influencing recovery. Ethics and dissemination The project was approved by the Monash University Human Research Ethics Committee project number 12 311. Results of this study will be submitted for publication in internationally peer-reviewed journals. The findings from this project have the capacity to improve the validity of paediatric injury burden measurements in future local and global burden of disease studies.

AB - Introduction Traumatic injury is a leading contributor to the global disease burden in children and adolescents, but methods used to estimate burden do not account for differences in patterns of injury and recovery between children and adults. A lack of empirical data on postinjury disability in children has limited capacity to derive valid disability weights and describe the long-term individual and societal impacts of injury in the early part of life. The aim of this study is to establish valid estimates of the burden of non-fatal injury in children and adolescents. Methods and analysis Five longitudinal studies of paediatric injury survivors 18 years at the time of injury (Australia, Canada, UK and USA) and two whole-of-population linked administrative data paediatric studies (Australia and Wales) will be analysed over a 3-year period commencing 2018. Meta-analysis of deidentified patient-level data (2,600) from five injury-specific longitudinal studies (Victorian State Trauma Registry; Victorian Orthopaedic Trauma Outcomes Registry; UK Burden of Injury; British Columbia Children's Hospital Longitudinal Injury Outcomes; Children's Health After Injury) and >1 million children from two whole-of-population cohorts (South Australian Early Childhood Data Project and Wales Electronic Cohort for Children). Systematic analysis of pooled injury-specific cohort data using a variety of statistical techniques, and parallel analysis of whole-of-population cohorts, will be used to develop estimated disability weights for years lost due to disability, establish appropriate injury classifications and explore factors influencing recovery. Ethics and dissemination The project was approved by the Monash University Human Research Ethics Committee project number 12 311. Results of this study will be submitted for publication in internationally peer-reviewed journals. The findings from this project have the capacity to improve the validity of paediatric injury burden measurements in future local and global burden of disease studies.

KW - epidemiology

KW - paediatrics

KW - public health

KW - trauma management

UR - http://www.scopus.com/inward/record.url?scp=85053147363&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2018-024755

DO - 10.1136/bmjopen-2018-024755

M3 - Article

VL - 8

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

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M1 - e024755

ER -