Abstract
Aptamers are nucleic acid sequences that can recognize and bind to analytes with high affinity and selectivity. Intriguingly, a number of aptamers undergo a conformational change within the G-quadruplex motif upon ligand binding. This Minireview aims to highlight interesting examples of luminescent G-quadruplex aptamer-based probes that have been developed in recent years. Various mechanisms and sensing modes are described, and the outlook and future directions of this field are also discussed.
Original language | English |
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Pages (from-to) | 8-17 |
Number of pages | 10 |
Journal | ChemPlusChem |
Volume | 82 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 2017 |
Keywords
- aptamers
- G-quadruplexes
- luminescence
- oligonucleotides
- sensors