Abstract
The excitability of the corticospinal tract can be quantified through the application of single-pulse transcranial magnetic stimulation (TMS) over the primary motor cortex (M1) and simultaneously recording the neurophysiological response at the target muscle through electromyography (EMG). In this chapter, we introduce the technique for constructing stimulusresponse (S-R) curves and the common methods employed to characterise the input-output properties of the corticospinal tract. We then describe the neurophysiological correlates of S-R curves and the physiological factors that can influence the TMS responses during the construction of an S-R curve, including age.
Original language | English |
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Title of host publication | A Closer Look at Motor-Evoked Potential |
Editors | Shapour Jaberzadeh |
Place of Publication | Hauppauge NY USA |
Publisher | Nova Science Publishers |
Chapter | 5 |
Pages | 77-91 |
Number of pages | 15 |
ISBN (Electronic) | 9781536143904 |
ISBN (Print) | 9781536143898 |
Publication status | Published - Jan 2019 |
Keywords
- input-output curve
- corticospinal excitability
- inhibition
- motor cortex
- motor evoked potential