We investigated the effectiveness of thyroid transcription factor-1 (TTF-1) as a helpful marker in the diagnosis of hepatocellular carcinoma (HCC). Cytoplasmic reactivity has been previously shown in both normal hepatocytes and neoplastic hepatocytes. We applied a non-biotin based immunohistochemical technique to reduce non-specific labelling and increase the sensitivity of TTF-1 staining in HCC.
|Pages (from-to)||11 - 14|
|Number of pages||4|
|Journal||Australian Journal of Medical Science|
|Publication status||Published - 2008|