Use of thyroid transcription factor-1 in the diagnosis of hepatocellular carcinoma

Simon Peter Nazaretian, P Nelva, Beena Kumar, B J Susil-Sumithran

Research output: Contribution to journalArticleResearchpeer-review


We investigated the effectiveness of thyroid transcription factor-1 (TTF-1) as a helpful marker in the diagnosis of hepatocellular carcinoma (HCC). Cytoplasmic reactivity has been previously shown in both normal hepatocytes and neoplastic hepatocytes. We applied a non-biotin based immunohistochemical technique to reduce non-specific labelling and increase the sensitivity of TTF-1 staining in HCC.
Original languageEnglish
Pages (from-to)11 - 14
Number of pages4
JournalAustralian Journal of Medical Science
Issue number1
Publication statusPublished - 2008

Cite this