Use of neostigmine in capecitabine-induced paralytic ileus

Gabriel Mak, Robyn L Ward, Yahya Shehabi, Ramya Venkateswaran, Melvin T. M. Chin

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


Paralytic ileus is a recognised side effect of the oral agent capecitabine. We present this report on a patient with metastatic colorectal cancer who was treated with capecitabine and presented with persistent paralytic ileus which did not respond to standard conservative measures. Neostigmine was administered safely, resulting in resolution of the paralytic ileus. This approach merits further investigation.

Original languageEnglish
Pages (from-to)e225-e228
Number of pages4
Issue number5
Publication statusPublished - Sept 2013
Externally publishedYes


  • Capecitabine
  • Neostigmine
  • Paralytic ileus

Cite this