Use of live attenuated Salmonella for oral vaccination

S. N. Chatfield, J. Li, G. Dougan, M. Roberts

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review


Several genetically defined live attenuated strains of Salmonella have been developed which are showing considerable promise as vaccines against salmonellosis in both animals and humans. Because such vaccines elicit a broad spectrum of immune responses they have been employed for delivering heterologous antigens to the mammalian immune system. Much effort has been put into constructing and evaluating attenuated Salmonella strains that can be practically used as delivery systems in humans and in developing systems that provide stable expression of heterologous antigens in vivo.

Original languageEnglish
Title of host publicationInstitution of Chemical Engineers Symposium Series
Editors Anon
PublisherInstitute of Chemical Engineers
Number of pages3
ISBN (Print)0852953356
Publication statusPublished - 1 Jan 1994
Externally publishedYes
EventProceedings of the 2nd Conference on Industrial Immunology - Brighton, UK
Duration: 4 Jul 19945 Jul 1994


ConferenceProceedings of the 2nd Conference on Industrial Immunology
CityBrighton, UK

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