Use of a radiopharmaceutical multidose dispenser for positron emission tomography: Risk assessment and mitigation measures for infection prevention

Daniela Karanfilovska, Ruth Martin, Howard Barton, Kenneth S. Yap, Allen Cheng

Research output: Contribution to journalComment / DebateOtherpeer-review


Positron emission tomography (PET) imaging necessitates the use of multidose vials for radiopharmaceutical delivery to patients. Conventional practices involve manual extraction of radiopharmaceuticals from a multidose vial prior to each PET procedure, which exposes the technologist to increasing levels of radiation and poses a potential infection risk to patients with frequent handling and access of the vial. New technologies for automated dosing and infusion delivery are available, however these incorporate both a multidose vial and a multi-patient infusion set. There is an absence of guidance for infection prevention (IP) units regarding the safety and acceptability of these devices. This paper describes the process of risk assessment and the mitigation measures for training, workflows, and documentation which led to the safe introduction of an automated PET infusion device in a large tertiary public healthcare facility.

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalInfection, Disease and Health
Issue number2
Publication statusPublished - Mar 2020


  • Infection control
  • Nuclear medicine
  • Positron-emission tomography
  • Radiation exposure
  • Radioactive tracer administration

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