Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.
- computed tomography
- kidney stone
Wong, P., Milat, F., Fuller, P. J., Kerr, P. G., Doery, J. C. G.
, Oh, D. H., ... Lau, K. K.
(2017). Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major
. Internal Medicine Journal
(9), 1064-1067. https://doi.org/10.1111/imj.13533