Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Phillip Wong; Frances Milat; Peter J. Fuller; Peter G. Kerr; James C. G. Doery; Danielle H. Oh; Dana Jackson; Matthew T. Gillespie; Donald K. Bowden; Sant-Rayn Pasricha; Kenneth K. Lau

doi:10.1111/imj.13533

Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Phillip Wong, Frances Milat, Peter J. Fuller, Peter G. Kerr, James C. G. Doery, Danielle H. Oh, Dana Jackson, Matthew T. Gillespie, Donald K. Bowden, Sant-Rayn Pasricha, Kenneth K. Lau

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.

Original language	English
Pages (from-to)	1064-1067
Number of pages	4
Journal	Internal Medicine Journal
Volume	47
Issue number	9
DOIs	https://doi.org/10.1111/imj.13533
Publication status	Published - Sep 2017

Keywords

computed tomography
kidney stone
osteoporosis
thalassaemia
urolithiasis

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10.1111/imj.13533

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Wong, Phillip ; Milat, Frances ; Fuller, Peter J. ; Kerr, Peter G. ; Doery, James C. G. ; Oh, Danielle H. ; Jackson, Dana ; Gillespie, Matthew T. ; Bowden, Donald K. ; Pasricha, Sant-Rayn ; Lau, Kenneth K. / Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major. In: Internal Medicine Journal. 2017 ; Vol. 47, No. 9. pp. 1064-1067.

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title = "Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major",

abstract = "Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.",

keywords = "computed tomography, kidney stone, osteoporosis, thalassaemia, urolithiasis",

author = "Phillip Wong and Frances Milat and Fuller, {Peter J.} and Kerr, {Peter G.} and Doery, {James C. G.} and Oh, {Danielle H.} and Dana Jackson and Gillespie, {Matthew T.} and Bowden, {Donald K.} and Sant-Rayn Pasricha and Lau, {Kenneth K.}",

year = "2017",

month = sep,

doi = "10.1111/imj.13533",

language = "English",

volume = "47",

pages = "1064--1067",

journal = "Internal Medicine Journal",

issn = "1444-0903",

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Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major. / Wong, Phillip; Milat, Frances ; Fuller, Peter J.; Kerr, Peter G.; Doery, James C. G.; Oh, Danielle H.; Jackson, Dana; Gillespie, Matthew T.; Bowden, Donald K.; Pasricha, Sant-Rayn; Lau, Kenneth K.

In: Internal Medicine Journal, Vol. 47, No. 9, 09.2017, p. 1064-1067.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

AU - Wong, Phillip

AU - Milat, Frances

AU - Fuller, Peter J.

AU - Kerr, Peter G.

AU - Doery, James C. G.

AU - Oh, Danielle H.

AU - Jackson, Dana

AU - Gillespie, Matthew T.

AU - Bowden, Donald K.

AU - Pasricha, Sant-Rayn

AU - Lau, Kenneth K.

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AB - Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.

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KW - osteoporosis

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JO - Internal Medicine Journal

JF - Internal Medicine Journal

SN - 1444-0903

IS - 9

ER -

Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Abstract

Keywords

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NHMRC Research Fellowship

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Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Abstract

Keywords

Access to Document

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Projects

NHMRC Research Fellowship

Cite this