Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Phillip Wong; Frances Milat; Peter J. Fuller; Peter G. Kerr; James C. G. Doery; Danielle H. Oh; Dana Jackson; Matthew T. Gillespie; Donald K. Bowden; Sant-Rayn Pasricha; Kenneth K. Lau

doi:10.1111/imj.13533

Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

Phillip Wong, Frances Milat, Peter J. Fuller, Peter G. Kerr, James C. G. Doery, Danielle H. Oh, Dana Jackson, Matthew T. Gillespie, Donald K. Bowden, Sant-Rayn Pasricha, Kenneth K. Lau

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Abstract

Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.

Original language	English
Pages (from-to)	1064-1067
Number of pages	4
Journal	Internal Medicine Journal
Volume	47
Issue number	9
DOIs	https://doi.org/10.1111/imj.13533
Publication status	Published - Sep 2017

Keywords

computed tomography
kidney stone
osteoporosis
thalassaemia
urolithiasis

Cite this

Wong, P., Milat, F., Fuller, P. J., Kerr, P. G., Doery, J. C. G., Oh, D. H., ... Lau, K. K. (2017). Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major. Internal Medicine Journal, 47(9), 1064-1067. https://doi.org/10.1111/imj.13533

Wong, Phillip ; Milat, Frances ; Fuller, Peter J. ; Kerr, Peter G. ; Doery, James C. G. ; Oh, Danielle H. ; Jackson, Dana ; Gillespie, Matthew T. ; Bowden, Donald K. ; Pasricha, Sant-Rayn ; Lau, Kenneth K. / Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major. In: Internal Medicine Journal. 2017 ; Vol. 47, No. 9. pp. 1064-1067.

@article{7445986cc59f4512b4b3627609761991,

title = "Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major",

abstract = "Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59{\%} and affected patients generally had multiple stones, often with more than one component: struvite (33{\%}), calcium oxalate (31{\%}) and cystine (22{\%}). Hypercalciuria was present in 78{\%} of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.",

keywords = "computed tomography, kidney stone, osteoporosis, thalassaemia, urolithiasis",

author = "Phillip Wong and Frances Milat and Fuller, {Peter J.} and Kerr, {Peter G.} and Doery, {James C. G.} and Oh, {Danielle H.} and Dana Jackson and Gillespie, {Matthew T.} and Bowden, {Donald K.} and Sant-Rayn Pasricha and Lau, {Kenneth K.}",

year = "2017",

month = "9",

doi = "10.1111/imj.13533",

language = "English",

volume = "47",

pages = "1064--1067",

journal = "Internal Medicine Journal",

issn = "1444-0903",

publisher = "Wiley-Blackwell",

number = "9",

}

Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major. / Wong, Phillip ; Milat, Frances ; Fuller, Peter J.; Kerr, Peter G.; Doery, James C. G.; Oh, Danielle H.; Jackson, Dana; Gillespie, Matthew T.; Bowden, Donald K.; Pasricha, Sant-Rayn; Lau, Kenneth K.

In: Internal Medicine Journal, Vol. 47, No. 9, 09.2017, p. 1064-1067.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

AU - Wong, Phillip

AU - Milat, Frances

AU - Fuller, Peter J.

AU - Kerr, Peter G.

AU - Doery, James C. G.

AU - Oh, Danielle H.

AU - Jackson, Dana

AU - Gillespie, Matthew T.

AU - Bowden, Donald K.

AU - Pasricha, Sant-Rayn

AU - Lau, Kenneth K.

PY - 2017/9

Y1 - 2017/9

N2 - Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.

AB - Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.

KW - computed tomography

KW - kidney stone

KW - osteoporosis

KW - thalassaemia

KW - urolithiasis

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U2 - 10.1111/imj.13533

DO - 10.1111/imj.13533

M3 - Article

AN - SCOPUS:85029029716

VL - 47

SP - 1064

EP - 1067

JO - Internal Medicine Journal

JF - Internal Medicine Journal

SN - 1444-0903

IS - 9

ER -

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10.1111/imj.13533

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Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major

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Keywords

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NHMRC Research Fellowship