Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link

Duk-Hee Kang; Jennifer Finch; Takahiko Nakagawa; S Ananth Karumanchi; John Kanellis; Joey Granger; Richard J Johnson

doi:10.1097/01.hjh.0000098227.37783.8e

Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link

Duk-Hee Kang, Jennifer Finch, Takahiko Nakagawa, S Ananth Karumanchi, John Kanellis, Joey Granger, Richard J Johnson

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Abstract

Background Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity. The hyperuricemia is believed to result primarily from the decreased renal excretion that occurs as a consequence of the pre-eclampsia, and as such is widely viewed as a marker for pre-eclampsia as opposed to having a role in the pathogenesis

Original language	English
Pages (from-to)	229 - 235
Number of pages	7
Journal	Journal of Hypertension
Volume	22
Issue number	2
DOIs	https://doi.org/10.1097/01.hjh.0000098227.37783.8e
Publication status	Published - 2004
Externally published	Yes

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10.1097/01.hjh.0000098227.37783.8e

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title = "Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link",

abstract = "Background Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity. The hyperuricemia is believed to result primarily from the decreased renal excretion that occurs as a consequence of the pre-eclampsia, and as such is widely viewed as a marker for pre-eclampsia as opposed to having a role in the pathogenesis",

author = "Duk-Hee Kang and Jennifer Finch and Takahiko Nakagawa and Karumanchi, {S Ananth} and John Kanellis and Joey Granger and Johnson, {Richard J}",

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T1 - Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link

AU - Kang, Duk-Hee

AU - Finch, Jennifer

AU - Nakagawa, Takahiko

AU - Karumanchi, S Ananth

AU - Kanellis, John

AU - Granger, Joey

AU - Johnson, Richard J

PY - 2004

Y1 - 2004

N2 - Background Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity. The hyperuricemia is believed to result primarily from the decreased renal excretion that occurs as a consequence of the pre-eclampsia, and as such is widely viewed as a marker for pre-eclampsia as opposed to having a role in the pathogenesis

AB - Background Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity. The hyperuricemia is believed to result primarily from the decreased renal excretion that occurs as a consequence of the pre-eclampsia, and as such is widely viewed as a marker for pre-eclampsia as opposed to having a role in the pathogenesis

UR - http://www.ncbi.nlm.nih.gov/pubmed/15076175

U2 - 10.1097/01.hjh.0000098227.37783.8e

DO - 10.1097/01.hjh.0000098227.37783.8e

M3 - Article

SN - 0263-6352

VL - 22

SP - 229

EP - 235

JO - Journal of Hypertension

JF - Journal of Hypertension

IS - 2

ER -

Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link

Abstract

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