Uric acid, endothelial dysfunction and pre-eclampsia: Searching for a pathogenetic link

Duk-Hee Kang, Jennifer Finch, Takahiko Nakagawa, S Ananth Karumanchi, John Kanellis, Joey Granger, Richard J Johnson

Research output: Contribution to journalArticleOther

81 Citations (Scopus)

Abstract

Background Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity. The hyperuricemia is believed to result primarily from the decreased renal excretion that occurs as a consequence of the pre-eclampsia, and as such is widely viewed as a marker for pre-eclampsia as opposed to having a role in the pathogenesis
Original languageEnglish
Pages (from-to)229 - 235
Number of pages7
JournalJournal of Hypertension
Volume22
Issue number2
DOIs
Publication statusPublished - 2004
Externally publishedYes

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