Projects per year
We report a high-resolution electrospray ionization mass spectrometric (HR ESI-MS) access route leading to in-depth insights into the spontaneous zwitterionic copolymerization mechanism between cyclic imino ethers (i.e., 2-methyl-2-oxazoline (MeOx), 2-ethyl-2-oxazoline (EtOx), or 2-ethyl-2-oxazine (EtOz)) with acrylic acid (AA), exploiting the characteristic species accumulating during the copolymerization as well as tandem mass spectrometry (MS/MS). We demonstrate preferences in α, ω-end group formation by screening various feed ratios of cyclic imino ethers and acrylic acid (e.g., MeOx:AA = 1:1; MeOx:AA = 2:1; and MeOx:AA = 1:2). Critically, a calibration curve - based on AA-MeOx-AA dimer - was established allowing for the semiquantitative determination of the end-group ratios with different feed ratios of acrylic acid. The formation of previously suggested alternating copolymers was confirmed by MS/MS experiments. Deviations from an ideal alternating composition were found to decrease from MeOx to EtOx to EtOz. The results of (semiquantitative) HR ESI-MS and MS/MS measurements suggest, for the first time presented in such precision, a polymerization mechanism for the spontaneous zwitterionic (alternating) copolymerization indicating optimal monomer ratios and pairings.
- 1 Finished
Davis, T., Boyd, B., Bunnett, N., Porter, C., Caruso, F., Kent, S., Thordarson, P., Kearnes, M., Gooding, J., Kavallaris, M., Thurecht, K., Whittaker, A., Parton, R., Corrie, S. R., Johnston, A., McGhee, J., Greguric, I. D., Stevens, M. M., Lewis, J., Lee, D. S., Alexander, C., Dawson, K., Hawker, C., Haddleton, D., Thierry, B., Prestidge, C. A., Meyer, A., Jones-Jayasinghe, N., Voelcker, N. H., Nann, T. & McLean, K.
Australian Research Council (ARC), Monash University, University of Melbourne, University of New South Wales, University of Queensland , University of South Australia, Monash University – Internal Faculty Contribution, University of Wisconsin Madison, Memorial Sloan Kettering Cancer Center, University of California System, University College Dublin, Imperial College London, University of Warwick, SungKyunKwan University, Australian Nuclear Science and Technology Organisation (ANSTO) , University of Nottingham
30/06/14 → 29/06/21