Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors

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  Mechanistic understanding of biased agonism and dimerisation for co-targeting incretin receptors for metabolic diseases

  Wootten, D. (Primary Chief Investigator (PCI))

  1/01/24 → 31/12/28

  Project: Research

• A personalised pharmacogenomic approach to inform autosomal dominant hypocalcaemia treatment

  Josephs, T. (Primary Chief Investigator (PCI))

  1/01/22 → 31/12/26

  Project: Research

• ARC Industrial Transformation Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery

  Sexton, P. (Primary Chief Investigator (PCI)), Rouiller, I. (Chief Investigator (CI)), Wootten, D. (Chief Investigator (CI)), van Oijen, A. (Chief Investigator (CI)), Parker, M. W. (Chief Investigator (CI)), Lucet, I. (Partner Investigator (PI)), Griffin, M. D. W. (Chief Investigator (CI)), Adams, D. J. (Chief Investigator (CI)), Czabotar, P. E. (Partner Investigator (PI)), Flocco, M. (Partner Investigator (PI)), Shepherd, R. K. (Partner Investigator (PI)), Ciferri, C. (Partner Investigator (PI)), Williams, P. A. (Partner Investigator (PI)), Brown, D. (Partner Investigator (PI)), Schreuder, H. (Partner Investigator (PI)), Reedtz-Runge, S. (Partner Investigator (PI)), Drinkwater, C. (Partner Investigator (PI)), Howard, B. L. (Partner Investigator (PI)), Betigeri, G. (Partner Investigator (PI)), Pryor, E. (Partner Investigator (PI)), How, J. (Project Manager), Pierce, T. (Chief Investigator (CI)) & Lees, J. (Partner Investigator (PI))

  Boehringer Ingelheim (Germany), AstraZeneca (United Kingdom)

  23/03/21 → 23/03/27

  Project: Research