Understanding the Roles of the NF-κB Pathway in Regulatory T Cell Development, Differentiation and Function

Thomas S. Fulford, Darcy Ellis, Steve Gerondakis

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

10 Citations (Scopus)

Abstract

The nuclear factor of kappaB (NF-κB) pathway has emerged as an important regulator of gene expression in CD4+ regulatory T cells. Here, we review various aspects of the roles NF-κB signaling plays in the development and function of Tregs.

Original languageEnglish
Title of host publicationRegulatory T Cells in Health and Disease, 2015
PublisherElsevier
Pages57-67
Number of pages11
Volume136
ISBN (Print)9780128034156
DOIs
Publication statusPublished - 2015

Publication series

NameProgress in Molecular Biology and Translational Science
Volume136
ISSN (Print)18771173
ISSN (Electronic)18780814

Keywords

  • C-Rel
  • Immune homeostasis
  • Nuclear factor kappaB
  • Treg development
  • Treg function

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