Uncovering protein–protein interactions through a team-based undergraduate biochemistry course

David L. Cookmeyer, Emily S. Winesett, Bashkim Kokona, Adam R. Huff, Sabina Aliev, Noah B. Bloch, Joshua A. Bulos, Irene L. Evans, Christian R. Fagre, Kerilyn N. Godbe, Maryna Khromava, Daniel M. Konstantinovsky, Alexander E. Lafrance, Alexandra J. Lamacki, Robert C. Parry, Jeanne M. Quinn, Alana M. Thurston, Kathleen J.S. Tsai, Aurelio Mollo, Max J. CryleRobert Fairman, Louise K. Charkoudian

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)


How can we provide fertile ground for students to simultaneously explore a breadth of foundational knowledge, develop cross-disciplinary problem-solving skills, gain resiliency, and learn to work as a member of a team? One way is to integrate original research in the context of an undergraduate biochemistry course. In this Community Page, we discuss the development and execution of an interdisciplinary and cross-departmental undergraduate biochemistry laboratory course. We present a template for how a similar course can be replicated at other institutions and provide pedagogical and research results from a sample module in which we challenged our students to study the binding interface between 2 important biosynthetic proteins. Finally, we address the community and invite others to join us in making a larger impact on undergraduate education and the field of biochemistry by coordinating efforts to integrate research and teaching across campuses.

Original languageEnglish
Article numbere2003145
Number of pages13
JournalPLoS Biology
Issue number11
Publication statusPublished - 1 Nov 2017

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