Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Abstract

Background: Ultrathin unsedated transnasal gastroscopy (UTEG) has a number of advantages applicable to eosinophilic esophagitis (EoE) and has not been evaluated for this condition. 

Aim: The aim of the study is to determine the feasibility of UTEG in patients with EoE and the acceptability of histological specimens obtained at biopsy. 

Method: All patients with a diagnosis of EoE presenting to the outpatients department of two hospitals (Box Hill Hospital and The Alfred Hospital, Melbourne Australia) were asked to participate in the study. UTEG was performed on consenting individuals. Feasibility was determined by the success of nasal intubaton, patient perception according to post procedural survey, and adequacy of esophageal biopsies was assessed. 

Results: Ninety-six consecutive patients with EoE were offered UTEG, and 24 agreed to participate in the study. Seventy-four UTEGs were performed over a period of 26months (September 2012 to December 2014). Nineteen patients had repeat procedures. Successful nasal intubation occurred in 97% (72 of 74 procedures), and 21 of 24 (86%) described high satisfaction with the procedure and minimal discomfort, and would choose UTEG for future procedures. Mean duration was 5min. Adverse events of epistaxis (three cases) and vomiting of liquid contents during the procedure (two cases) were recorded, cardiorespiratory parameters remaining normal in all patients. All completed procedures produced adequate histological samples. 

Conclusion: In those who decide to undergo UTEG, it is a safe and well-tolerated procedure.

Original languageEnglish
Pages (from-to)590-594
Number of pages5
JournalJournal of Gastroenterology and Hepatology
Volume31
Issue number3
DOIs
Publication statusPublished - 1 Mar 2016

Keywords

  • Biopsy
  • Eosinophilic esophagitis
  • Gastroscopy
  • Transnasal

Cite this

@article{f489026a1b36437d9e841657d187f85d,
title = "Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis",
abstract = "Background: Ultrathin unsedated transnasal gastroscopy (UTEG) has a number of advantages applicable to eosinophilic esophagitis (EoE) and has not been evaluated for this condition. Aim: The aim of the study is to determine the feasibility of UTEG in patients with EoE and the acceptability of histological specimens obtained at biopsy. Method: All patients with a diagnosis of EoE presenting to the outpatients department of two hospitals (Box Hill Hospital and The Alfred Hospital, Melbourne Australia) were asked to participate in the study. UTEG was performed on consenting individuals. Feasibility was determined by the success of nasal intubaton, patient perception according to post procedural survey, and adequacy of esophageal biopsies was assessed. Results: Ninety-six consecutive patients with EoE were offered UTEG, and 24 agreed to participate in the study. Seventy-four UTEGs were performed over a period of 26months (September 2012 to December 2014). Nineteen patients had repeat procedures. Successful nasal intubation occurred in 97{\%} (72 of 74 procedures), and 21 of 24 (86{\%}) described high satisfaction with the procedure and minimal discomfort, and would choose UTEG for future procedures. Mean duration was 5min. Adverse events of epistaxis (three cases) and vomiting of liquid contents during the procedure (two cases) were recorded, cardiorespiratory parameters remaining normal in all patients. All completed procedures produced adequate histological samples. Conclusion: In those who decide to undergo UTEG, it is a safe and well-tolerated procedure.",
keywords = "Biopsy, Eosinophilic esophagitis, Gastroscopy, Transnasal",
author = "Hamish Philpott and Sanjay Nandurkar and Royce, {Simon G.} and Gibson, {Peter R.}",
year = "2016",
month = "3",
day = "1",
doi = "10.1111/jgh.13173",
language = "English",
volume = "31",
pages = "590--594",
journal = "Journal of Gastroenterology and Hepatology",
issn = "0815-9319",
publisher = "Wiley-Blackwell",
number = "3",

}

Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis. / Philpott, Hamish; Nandurkar, Sanjay; Royce, Simon G.; Gibson, Peter R.

In: Journal of Gastroenterology and Hepatology, Vol. 31, No. 3, 01.03.2016, p. 590-594.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis

AU - Philpott, Hamish

AU - Nandurkar, Sanjay

AU - Royce, Simon G.

AU - Gibson, Peter R.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Background: Ultrathin unsedated transnasal gastroscopy (UTEG) has a number of advantages applicable to eosinophilic esophagitis (EoE) and has not been evaluated for this condition. Aim: The aim of the study is to determine the feasibility of UTEG in patients with EoE and the acceptability of histological specimens obtained at biopsy. Method: All patients with a diagnosis of EoE presenting to the outpatients department of two hospitals (Box Hill Hospital and The Alfred Hospital, Melbourne Australia) were asked to participate in the study. UTEG was performed on consenting individuals. Feasibility was determined by the success of nasal intubaton, patient perception according to post procedural survey, and adequacy of esophageal biopsies was assessed. Results: Ninety-six consecutive patients with EoE were offered UTEG, and 24 agreed to participate in the study. Seventy-four UTEGs were performed over a period of 26months (September 2012 to December 2014). Nineteen patients had repeat procedures. Successful nasal intubation occurred in 97% (72 of 74 procedures), and 21 of 24 (86%) described high satisfaction with the procedure and minimal discomfort, and would choose UTEG for future procedures. Mean duration was 5min. Adverse events of epistaxis (three cases) and vomiting of liquid contents during the procedure (two cases) were recorded, cardiorespiratory parameters remaining normal in all patients. All completed procedures produced adequate histological samples. Conclusion: In those who decide to undergo UTEG, it is a safe and well-tolerated procedure.

AB - Background: Ultrathin unsedated transnasal gastroscopy (UTEG) has a number of advantages applicable to eosinophilic esophagitis (EoE) and has not been evaluated for this condition. Aim: The aim of the study is to determine the feasibility of UTEG in patients with EoE and the acceptability of histological specimens obtained at biopsy. Method: All patients with a diagnosis of EoE presenting to the outpatients department of two hospitals (Box Hill Hospital and The Alfred Hospital, Melbourne Australia) were asked to participate in the study. UTEG was performed on consenting individuals. Feasibility was determined by the success of nasal intubaton, patient perception according to post procedural survey, and adequacy of esophageal biopsies was assessed. Results: Ninety-six consecutive patients with EoE were offered UTEG, and 24 agreed to participate in the study. Seventy-four UTEGs were performed over a period of 26months (September 2012 to December 2014). Nineteen patients had repeat procedures. Successful nasal intubation occurred in 97% (72 of 74 procedures), and 21 of 24 (86%) described high satisfaction with the procedure and minimal discomfort, and would choose UTEG for future procedures. Mean duration was 5min. Adverse events of epistaxis (three cases) and vomiting of liquid contents during the procedure (two cases) were recorded, cardiorespiratory parameters remaining normal in all patients. All completed procedures produced adequate histological samples. Conclusion: In those who decide to undergo UTEG, it is a safe and well-tolerated procedure.

KW - Biopsy

KW - Eosinophilic esophagitis

KW - Gastroscopy

KW - Transnasal

UR - http://www.scopus.com/inward/record.url?scp=84959107052&partnerID=8YFLogxK

U2 - 10.1111/jgh.13173

DO - 10.1111/jgh.13173

M3 - Article

VL - 31

SP - 590

EP - 594

JO - Journal of Gastroenterology and Hepatology

JF - Journal of Gastroenterology and Hepatology

SN - 0815-9319

IS - 3

ER -