Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors

Ossama El-Kabbani; Connie Darmanin; Thomas R Schneider; Isabelle Hazemann; Federico Ruiz; Mitsuru Oka; Andrzejj Joachimiak; Clemens Schulze-Briese; Takashi Tomizaki; Andre Mitschler; Alberto D Podjarny

doi:10.1002/prot.20001

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors

Ossama El-Kabbani, Connie Darmanin, Thomas R Schneider, Isabelle Hazemann, Federico Ruiz, Mitsuru Oka, Andrzejj Joachimiak, Clemens Schulze-Briese, Takashi Tomizaki, Andre Mitschler, Alberto D Podjarny

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

88 Citations (Scopus)

Original language	English
Pages (from-to)	805 - 813
Number of pages	9
Journal	Proteins: Structure, Function and Bioinformatics
Volume	55
Issue number	4
DOIs	https://doi.org/10.1002/prot.20001
Publication status	Published - 2004

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10.1002/prot.20001

Cite this

El-Kabbani, O., Darmanin, C., Schneider, T. R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., & Podjarny, A. D. (2004). Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors. Proteins: Structure, Function and Bioinformatics, 55(4), 805 - 813. https://doi.org/10.1002/prot.20001

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title = "Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors",

author = "Ossama El-Kabbani and Connie Darmanin and Schneider, {Thomas R} and Isabelle Hazemann and Federico Ruiz and Mitsuru Oka and Andrzejj Joachimiak and Clemens Schulze-Briese and Takashi Tomizaki and Andre Mitschler and Podjarny, {Alberto D}",

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language = "English",

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El-Kabbani, O, Darmanin, C, Schneider, TR, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A & Podjarny, AD 2004, 'Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors', Proteins: Structure, Function and Bioinformatics, vol. 55, no. 4, pp. 805 - 813. https://doi.org/10.1002/prot.20001

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors. / El-Kabbani, Ossama; Darmanin, Connie; Schneider, Thomas R et al.
In: Proteins: Structure, Function and Bioinformatics, Vol. 55, No. 4, 2004, p. 805 - 813.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors

AU - El-Kabbani, Ossama

AU - Darmanin, Connie

AU - Schneider, Thomas R

AU - Hazemann, Isabelle

AU - Ruiz, Federico

AU - Oka, Mitsuru

AU - Joachimiak, Andrzejj

AU - Schulze-Briese, Clemens

AU - Tomizaki, Takashi

AU - Mitschler, Andre

AU - Podjarny, Alberto D

PY - 2004

Y1 - 2004

U2 - 10.1002/prot.20001

DO - 10.1002/prot.20001

M3 - Article

SN - 0887-3585

VL - 55

SP - 805

EP - 813

JO - Proteins: Structure, Function and Bioinformatics

JF - Proteins: Structure, Function and Bioinformatics

IS - 4

ER -

El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M et al. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors. Proteins: Structure, Function and Bioinformatics. 2004;55(4):805 - 813. doi: 10.1002/prot.20001