Abstract
Ulcerative colitis (UC) and Crohn's disease (CD) represent the two major forms of inflammatory bowel disease (IBD). UC is a chronic idiopathic inflammatory condition affecting the colon and rectum. A complex interplay between components of the innate immune system and environmental factors, notably the microflora, regulates colonic mucosal homeostasis, which is dysregulated in UC. In this chapter, we review current concepts of the epidemiology, pathogenesis, clinical features and management of UC.
Original language | English |
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Pages (from-to) | 276-281 |
Number of pages | 6 |
Journal | Medicine |
Volume | 43 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1 Jan 2015 |
Externally published | Yes |
Keywords
- inflammatory bowel disease
- management
- pathogenesis
- ulcerative colitis