Ulcerative colitis

Gwo Tzer Ho, Ray Boyapati, Jack Satsangi

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

Abstract

Ulcerative colitis (UC) and Crohn's disease (CD) represent the two major forms of inflammatory bowel disease (IBD). UC is a chronic idiopathic inflammatory condition affecting the colon and rectum. A complex interplay between components of the innate immune system and environmental factors, notably the microflora, regulates colonic mucosal homeostasis, which is dysregulated in UC. In this chapter, we review current concepts of the epidemiology, pathogenesis, clinical features and management of UC.

Original languageEnglish
Pages (from-to)276-281
Number of pages6
JournalMedicine
Volume43
Issue number5
DOIs
Publication statusPublished - 1 Jan 2015
Externally publishedYes

Keywords

  • inflammatory bowel disease
  • management
  • pathogenesis
  • ulcerative colitis

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