Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

Karly C. Sourris; Brooke E. Harcourt; Peter Tang; Amy Morley; Karina Huynh; Sally A. Penfold; Melinda T. Coughlan; Mark E. Cooper; Tuong-Vi Nguyen; Rebecca H. Ritchie; Josephine M. Forbes

doi:10.1016/j.freeradbiomed.2011.11.017

Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

Karly C. Sourris, Brooke E. Harcourt, Peter Tang, Amy Morley, Karina Huynh, Sally A. Penfold, Melinda T. Coughlan, Mark E. Cooper, Tuong-Vi Nguyen, Rebecca H. Ritchie, Josephine M. Forbes

Research output: Contribution to journal › Article › Research › peer-review

100 Citations (Scopus)

Abstract

Cardiovascular benefits of ubiquinone have been previously demonstrated, and we administered it as a novel therapy in an experimental model of type 2 diabetic nephropathy

Original language	English
Pages (from-to)	716 - 723
Number of pages	8
Journal	Free Radical Biology and Medicine
Volume	52
Issue number	3
DOIs	https://doi.org/10.1016/j.freeradbiomed.2011.11.017
Publication status	Published - 2012

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10.1016/j.freeradbiomed.2011.11.017

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Sourris, K. C., Harcourt, B. E., Tang, P., Morley, A., Huynh, K., Penfold, S. A., Coughlan, M. T., Cooper, M. E., Nguyen, T-V., Ritchie, R. H., & Forbes, J. M. (2012). Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. Free Radical Biology and Medicine, 52(3), 716 - 723. https://doi.org/10.1016/j.freeradbiomed.2011.11.017

Sourris, Karly C. ; Harcourt, Brooke E. ; Tang, Peter ; Morley, Amy ; Huynh, Karina ; Penfold, Sally A. ; Coughlan, Melinda T. ; Cooper, Mark E. ; Nguyen, Tuong-Vi ; Ritchie, Rebecca H. ; Forbes, Josephine M. / Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. In: Free Radical Biology and Medicine. 2012 ; Vol. 52, No. 3. pp. 716 - 723.

@article{1e3b4cca7b55464aaca2daa2be71c811,

title = "Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes",

abstract = "Cardiovascular benefits of ubiquinone have been previously demonstrated, and we administered it as a novel therapy in an experimental model of type 2 diabetic nephropathy",

author = "Sourris, {Karly C.} and Harcourt, {Brooke E.} and Peter Tang and Amy Morley and Karina Huynh and Penfold, {Sally A.} and Coughlan, {Melinda T.} and Cooper, {Mark E.} and Tuong-Vi Nguyen and Ritchie, {Rebecca H.} and Forbes, {Josephine M.}",

year = "2012",

doi = "10.1016/j.freeradbiomed.2011.11.017",

language = "English",

volume = "52",

pages = "716 -- 723",

journal = "Free Radical Biology and Medicine",

issn = "0891-5849",

publisher = "Elsevier",

number = "3",

}

Sourris, KC, Harcourt, BE, Tang, P, Morley, A, Huynh, K, Penfold, SA, Coughlan, MT , Cooper, ME, Nguyen, T-V, Ritchie, RH & Forbes, JM 2012, 'Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes', Free Radical Biology and Medicine, vol. 52, no. 3, pp. 716 - 723. https://doi.org/10.1016/j.freeradbiomed.2011.11.017

Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. / Sourris, Karly C.; Harcourt, Brooke E.; Tang, Peter; Morley, Amy; Huynh, Karina; Penfold, Sally A.; Coughlan, Melinda T.; Cooper, Mark E.; Nguyen, Tuong-Vi; Ritchie, Rebecca H.; Forbes, Josephine M.

In: Free Radical Biology and Medicine, Vol. 52, No. 3, 2012, p. 716 - 723.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

AU - Sourris, Karly C.

AU - Harcourt, Brooke E.

AU - Tang, Peter

AU - Morley, Amy

AU - Huynh, Karina

AU - Penfold, Sally A.

AU - Coughlan, Melinda T.

AU - Cooper, Mark E.

AU - Nguyen, Tuong-Vi

AU - Ritchie, Rebecca H.

AU - Forbes, Josephine M.

PY - 2012

Y1 - 2012

N2 - Cardiovascular benefits of ubiquinone have been previously demonstrated, and we administered it as a novel therapy in an experimental model of type 2 diabetic nephropathy

AB - Cardiovascular benefits of ubiquinone have been previously demonstrated, and we administered it as a novel therapy in an experimental model of type 2 diabetic nephropathy

UR - http://www.sciencedirect.com/science/article/pii/S0891584911012044

U2 - 10.1016/j.freeradbiomed.2011.11.017

DO - 10.1016/j.freeradbiomed.2011.11.017

M3 - Article

VL - 52

SP - 716

EP - 723

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

SN - 0891-5849

IS - 3

ER -

Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

Abstract

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