Typing of methicillin-resistant Staphylococcus aureus by antibiotic resistance phenotypes

M. T. Gillespie, B. R. Lyon, R. A. Skurray

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The identification of new epidemic strains of methicillin-resistant Staphylococcus aureus is essential for rapid, effective infection control. We have developed a typing method which uses antibiotic sensitivity patterns to differentiate methicillin-resistant S. aureus and which is faster and more cost-effective than biochemical analysis or bacteriophage typing. Characterisation of phenotypes which are chromosomally-encoded, plasmid- or chromosomally-encoded or exclusively plasmid-mediated has enabled us to separate Australian strains of methicillin-resistant S. aureus into 11 classes, representatives of which were indistinguishable by bacteriophage type, or plasmid profile alone. The value of this procedure is thus clearly shown.

Original languageEnglish
Pages (from-to)57-64
Number of pages8
JournalJournal of Medical Microbiology
Issue number1
Publication statusPublished - 1 Jan 1990

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