Two cases of arteriovenous hemangioma associated with chronic liver diseases

Fumihito Noguchi, Iriko Oshima, Sachiko Higashi, Maki Nagamatsu, Aya Ikeda, Akiko Miyazaki, Kentaro Ozawa, Taketsugu Tadokoro

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We report here two cases of arteriovenous hemangioma. (i) A 59-year-old man who had suffered from chronic liver dysfunction for about 20 years and was diagnosed with liver cirrhosis associated with chronic hepatitis C 5 years ago; (ii) A 70-year-old woman who had suffered from chronic hepatitis C for about 20 years. The first patient showed asymptomatic reddish round nodules on the right side of the lower jaw. The second patient showed an asymptomatic reddish round nodule on the nose. Histopathological analysis of the tumors revealed aggregates of proliferating blood vessels, consisting of intermingling thick- and thin-walled vessels in the dermis lined with a single layer of endothelial cells. Elastic van Gieson staining showed no apparent internal elastic lamina but thin elastic fiber in the thick-walled artery-like vessels. These clinical and pathological findings were consistent with the diagnosis of AVH. Although the pathogenesis of AVH is unknown, several cases of AVH associated with chronic liver diseases have been described and it has been suggested that AVH may be a noteworthy dermadrome of chronic liver diseases.

Original languageEnglish
Pages (from-to)500-504
Number of pages5
JournalSkin Research
Issue number6
Publication statusPublished - 1 Dec 2011
Externally publishedYes


  • Arteriovenous hemangioma
  • Dermadorome
  • Liver cirrhosis

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