Turn up the HEAT

Bostjan Kobe, Thomas Gleichmann, James Horne, Ian G. Jennings, Pierre D. Scotney, Trazel Teh

Research output: Contribution to journalReview ArticleResearchpeer-review

56 Citations (Scopus)

Abstract

The recently determined crystal structure of the PR65/A subunit of protein phosphatase 2A reveals the architecture of proteins containing HEAT repeats. The structural properties of this solenoid protein explain many functional characteristics and account for the involvement of solenoids as scaffold, anchoring and adaptor proteins.

Original languageEnglish
Pages (from-to)R91-R97
JournalStructure
Volume7
Issue number5
DOIs
Publication statusPublished - 5 May 1999
Externally publishedYes

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