Tumor Lysis Syndrome

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Tumor lysis syndrome refers to the laboratory and clinical results of rapid breakdown of high volumes of malignant cells. Significant electrolyte disturbances, particularly hyperkalemia, hypocalcemia, and hyperphosphatemia, in tandem with severe hyperuricemia, are disease hallmarks. The most significant clinical sequelae of these disturbances include life-threatening cardiac arrhythmias, sudden death, seizures, and renal failure due to precipitation of uric acid or calcium phosphate in the renal tubules.
Original languageEnglish
Title of host publicationTextbook of Palliative Care
EditorsRoderick Duncan MacLeod, Lieve van den Block
Place of PublicationCham
Number of pages15
ISBN (Electronic)9783319317380
Publication statusPublished - 2018

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