T1 Mapping Techniques in Assessment of Ventricular Stiffness

Andris H. Ellims; Andrew J. Taylor

doi:10.1007/s12410-014-9318-5

T₁ Mapping Techniques in Assessment of Ventricular Stiffness

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

Myocardial fibrosis is a fundamental process in the development of heart failure and can be quantified by cardiac magnetic resonance (CMR) imaging with T₁ mapping techniques. By measuring post-contrast myocardial T₁ time and obtaining invasively determined ventricular pressure-volume data, a mechanistic link between diffuse myocardial fibrosis and increased ventricular stiffness has recently been identified. The capacity to non-invasively evaluate diffuse myocardial fibrosis may enhance our understanding of cardiac diseases and facilitate trials of novel therapies.

Original language	English
Article number	1
Number of pages	7
Journal	Current Cardiovascular Imaging Reports
Volume	8
Issue number	2
DOIs	https://doi.org/10.1007/s12410-014-9318-5
Publication status	Published - 1 Jan 2015
Externally published	Yes

Keywords

Cardiac magnetic resonance
Heart failure
Myocardial fibrosis
T mapping
Ventricular stiffness

Access to Document

10.1007/s12410-014-9318-5

Cite this

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title = "T1 Mapping Techniques in Assessment of Ventricular Stiffness",

abstract = "Myocardial fibrosis is a fundamental process in the development of heart failure and can be quantified by cardiac magnetic resonance (CMR) imaging with T1 mapping techniques. By measuring post-contrast myocardial T1 time and obtaining invasively determined ventricular pressure-volume data, a mechanistic link between diffuse myocardial fibrosis and increased ventricular stiffness has recently been identified. The capacity to non-invasively evaluate diffuse myocardial fibrosis may enhance our understanding of cardiac diseases and facilitate trials of novel therapies.",

keywords = "Cardiac magnetic resonance, Heart failure, Myocardial fibrosis, T mapping, Ventricular stiffness",

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AB - Myocardial fibrosis is a fundamental process in the development of heart failure and can be quantified by cardiac magnetic resonance (CMR) imaging with T1 mapping techniques. By measuring post-contrast myocardial T1 time and obtaining invasively determined ventricular pressure-volume data, a mechanistic link between diffuse myocardial fibrosis and increased ventricular stiffness has recently been identified. The capacity to non-invasively evaluate diffuse myocardial fibrosis may enhance our understanding of cardiac diseases and facilitate trials of novel therapies.

KW - Cardiac magnetic resonance

KW - Heart failure

KW - Myocardial fibrosis

KW - T mapping

KW - Ventricular stiffness

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DO - 10.1007/s12410-014-9318-5

M3 - Review Article

AN - SCOPUS:84922324418

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VL - 8

JO - Current Cardiovascular Imaging Reports

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