Trends and variation in prostate cancer diagnosis via transperineal biopsy in Australia and New Zealand

Michael E. O' Callaghan, Matthew Roberts, Jeremy Grummet, Stephen Mark, Daniel Gilbourd, Mark Frydenberg, Jeremy Millar, Nathan Papa, on behalf of the Prostate Cancer Outcomes Registry of Australia and New Zealand (PCOR-ANZ)

Research output: Contribution to journalArticleResearchpeer-review


Background: To describe changes in the use of prostate biopsy techniques among men diagnosed with prostate cancer in Australia and New Zealand and examine factors associated with these changes. Methods: We extracted data between 2015 and 2019 from 7 jurisdictions of the Australia and New Zealand Prostate Cancer Outcomes Registry (PCOR-ANZ). Distribution and time trend of transrectal (TR) vs. transperineal (TP) biopsy type, differences in the proportion of biopsy type by geographic jurisdiction, diagnosing institute characteristics (public vs. private, metropolitan vs. regional, case volume) and patient characteristics such as socio-economic status (SES), and location of residence were analyzed. Results: We analyzed data from 37,638 patients. The overall proportion of prostate cancer diagnosed by TP increased from 26% to 57% between 2015 and 2019. Patients living in a major city, a more socioeconomically advantaged area or who were diagnosed in a metropolitan or private hospital were more likely to have TP than TR. While all subgroups were observed to increase their use of TP over the study period, uptake grew faster for men from low SES areas and those diagnosed at a regional or low-volume hospital but slower for men living in outer regional/remote areas or treated at a public hospital. Conclusions: In this binational registry, prostate cancer is now more commonly diagnosed by TP than the TR approach. While the gap between uptakes of TP has diminished for patients with low vs. high SES, disparity has widened for patients from outer regional areas vs major cities and public vs. private hospitals.

Original languageEnglish
Pages (from-to)324.e13-324.e20
Number of pages8
JournalUrologic Oncology: Seminars and Original Investigations
Issue number7
Publication statusPublished - Jul 2023


  • Biopsy
  • Prostate cancer
  • Registry
  • Transperineal
  • TRUS
  • Urology

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