Treatment outcomes of alginate-embedded allogenic mesenchymal stem cells versus autologous chrondrocytes for the repair of focal articular cartilage defects in a rabbit model

Liang Xin Tay, Raja Elina Ahmad, Havva Dashtdar, K W Tay, T Masjuddin, S Ab-Rahim, Pan Pan Chong, Lakshmi Selvaratnam, Tunku Kamarul

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    64 Citations (Scopus)

    Abstract

    Mesenchymal stem cells (MSCs) represent a promising alternative form of cell-based therapy for cartilage injury. However, the capacity of MSCs for chondrogenesis has not been fully explored. In particular, there is presently a lack of studies comparing the effectiveness of MSCs to conventional autologous chondrocyte (autoC) treatment for regeneration of full-thickness cartilage defects in vivo.
    Original languageEnglish
    Pages (from-to)83 - 90
    Number of pages8
    JournalThe American Journal of Sports Medicine
    Volume4
    Issue number1
    DOIs
    Publication statusPublished - 2012

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