Treatment of camptocormia with botulinum toxin

Kelly L Bertram, Paola Stirpe, Carlo Colosimo

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

Camptocormia is defined as an involuntary axial postural distortion of >45 flexion which occurs in the upright position, increases whilst walking and resolves when supine (Ashour and Jankovic, 2006). Unlikeorthopaedic or age related kyphosis it is not a fixed structural deformity and produces kyphosis at predominantly lumbar and thoracic rather than cervical regions. Camptocormia has been reported due to a wide range of neurologic, psychiatric, muscular and orthopaedic conditions as well as rare reports of its emergence following the initiation of a number ofmedications (Finsterer and Strobl, 2010). Parkinson s disease (PD) includes prominent motor features of bradykinesia, rigidity and reducedpostural balance responses in all those affected with this disease, but can also cause a range of other motor and non-motor features. Camptocormia is reported in a minority of patients with PD, and it isusually associated with longer disease duration and greater disease burden (Tiple et al., 2009). The aetiology of camptocormia in PD is debated, and responses to treatment have been generally poor andvariable between studies. Recent studies have suggested the use of botulinum toxin may improve posture in some affected individuals.
Original languageEnglish
Pages (from-to)148-153
Number of pages6
JournalToxicon : official journal of the International Society on Toxinology
Volume107
DOIs
Publication statusPublished - 1 Dec 2015

Keywords

  • botulinum toxin
  • camptocormia
  • Parkinson's desease

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