Translocation of proteins into mitochondria

N. J. Hoogenraad, M. T. Ryan

Research output: Contribution to journalReview ArticleResearchpeer-review

14 Citations (Scopus)

Abstract

The translocase of the outer mitochondrial membrane (TOM) is composed of receptors, a channel protein, and its modulators that function together to import proteins into mitochondria. Although the import pathway of proteins directed to the mitochondrial matrix has been well characterized, recent studies into the import pathway taken by proteins into the other submitochondrial compartments have broadened our understanding into the way the TOM machinery recognizes, interacts, and translocates proteins.

Original languageEnglish
Pages (from-to)345-350
Number of pages6
JournalIUBMB Life
Volume51
Issue number6
DOIs
Publication statusPublished - 10 Dec 2001
Externally publishedYes

Keywords

  • Import
  • Mitochondria
  • TIM
  • TOM
  • Trafficking

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